Op 8 januari 2020 verdedigde Jelmer Brouwer zijn proefschrift 'Detection, detention, deportation'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.P. van der Leun en prof.dr. M.A.H. van der Woude.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Promotor: I. Snellen, Co-Promotor: M. Kenworthy

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

How do nanoparticles bioaccumulate and biodistribute in organisms?

Cardiovascular diseases (CVDs) are the leading global cause of mortality. Endothelial dysfunction, an early reversible stage of CVD development, is marked by decreased nitric oxide production linked to Ca2+ influx in endothelial cells.

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

Promotor: A.W. van der Vaart

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

In this work, we attempt to answer the question:

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…

Promotie

The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

Promotor: M.A.G.J. Orrit

Promotie

Promotie

Promotie

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

LiDAR is een relatief nieuwe meettechniek waarmee het Actueel Hoogtebestand Nederland het hele land zeer nauwkeurig mee heeft ingemeten. Het grote voordeel van deze manier van meten is dat vegetatie geen belemmering vormt. Hierdoor kunnen ook gebieden waar vegetatie de zichtbaarheid van de ondergrond…

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Promotor: Prof.dr. T. Hankemeier

Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

One of the most important correlation functions in physics, especially in cosmology, is the energy density, which describes how much energy is present at each point in spacetime due to matter fields. A key contribution to the energy density of the primordial universe comes from gravitational waves (GWs),…

We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel