484 zoekresultaten voor “vascular and regenerative medicine” in de Publieke website
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Small regulatory RNAs in Vascular Remodeling and Atherosclerosis
Promotie
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
- Technical Medicine diploma uitreiking
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Macrophage activation and cholesterol in atherosclerosis development
Current therapies for patients with atherosclerosis are targeted primarily on reducing blood cholesterol, but this fails to prevent a large number of cardiovascular events.95 In order to identify new therapeutic strategies for treating atherosclerosis, it is important to study the interactions between…
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Macrophage activation and cholesterol in atherosclerosis development
Promotores:Th.J.C. van Berkel, M. van Eck
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
- Diploma-uitreiking Technical Medicine
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Risk stratification in Emergency Medicine
Promotie
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Personalized medicine in rheumatoid arthritis
Promotie
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Near-infrared fluorescence imaging with indocyanine green in vascular surgery
Promotie
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Short-term Pre-operative Dietary Restriction in Vascular Surgery
Promotie
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Vascular and structural neuroimaging findings in migraine and RVCL-S
Promotie
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Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union
1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…
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Understanding the role of mycorrhizas in global carbon cycle processes
How the global distribution of vegetation stands dominated by arbuscular and ectomycorrhizal plants relate to principle aspects of belowground carbon accumulation processes?
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Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
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Do fungi differ? Understanding the mechanisms of mycorrhizal fungal impacts on soil C sequestration
How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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What’s CLIL about bilingual education? A window on Content and Language Integrated Learning pedagogies
In Nederland bieden ongeveer 130 van de 700 middelbare scholen een tweetalige stroom aan. Toch is er nog maar weinig wetenschappelijk onderzoek naar CLIL (content and language integrated learning). Met haar proefschrift wil Evelyn van Kampen (promovendus bij het ICLON) bijdragen aan een beter begrip…
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Onderwijs
In het Leids Universitair Medisch Centrum (LUMC) word je klaargestoomd voor de wereld van morgen. We brengen op een unieke manier onderzoek en patiëntenzorg samen in ons onderwijs.
- Diploma-uitreiking MSc Technical Medicine
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Modeling vascular disease using self-assembling human induced pluripotent stem cell derivatives in 3D vessels-on-chip
Promotie
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Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
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pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Freezing conditions in warm disks: snowlines and their effect on the chemical structure of planet-forming disks
This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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Hersens reageren anders dan verwacht op ADHD-medicijn
Een beproefd medicijn voor de behandeling van ADHD werkt in de hersenen van gezonde niet-actieve personen net andersom dan werd gedacht: het stimuleert de hersenactiviteit niet maar onderdrukt deze juist. Publicatie in The Journal of Neuroscience op 27 juli.
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Haico van Attikum
Faculteit Geneeskunde
h.van.attikum@lumc.nl | +31 71 526 9624
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Céline Zaepffel
Faculteit der Geesteswetenschappen
c.v.zaepffel@hum.leidenuniv.nl | +31 71 527 2050
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Cornelis Hokke
Faculteit Geneeskunde
c.h.hokke@lumc.nl | +31 71 526 5065
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
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Knowledge of Medicinal, Aromatic and Cosmetic (MAC) Plants in the Utilisation of the Plural Medical System in Pirgos and Praitoria for Community Health
Promotor: Prof.dr. L.J. Slikkerveer
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Online Course Clinical Kidney, Pancreas and Islet Transplantation
Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.
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LUMC bouwt grootste stamcelfaciliteit voor Nederland
Het Leids Universitair Medisch Centrum (LUMC) start dit jaar met de bouw van de grootste non-profit stamcel- en gentherapiefaciliteit van Nederland, en een van de grootste faciliteiten in Europa. In het NECSTGEN, het Netherlands Center for the Clinical advancement of Stemcell and Gene Therapies, wordt…
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The details of past actions on a smartphone touchscreen are reflected by intrinsic sensorimotor dynamics
Unconstrained day-to-day activities are difficult to quantify and how the corresponding movements shape the brain remain unclear. Read more
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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Medicijnontwikkeling is zoeken naar magic bullets
Geneesmiddelen worden steeds preciezer en innovatiever, maar ook steeds duurder. Aan universiteiten de taak om met hun innovaties meer competitie en daardoor lagere prijzen te bewerkstelligen. Dat betoogt Hubertus Irth, de nieuwe hoogleraar Biomoleculaire analyse. Oratie op 4 december.
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Paul Wouters
Faculteit der Sociale Wetenschappen
p.f.wouters@fsw.leidenuniv.nl | +31 71 527 2727
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Jian Wang
Faculteit der Sociale Wetenschappen
j.wang@cwts.leidenuniv.nl | +31 71 527 2727
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Vincent Chang
Faculteit der Geesteswetenschappen
v.k.chang@hum.leidenuniv.nl | +31 71 527 2151
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Extreem overgewicht vraagt om medicatie op maat
Artsen en apothekers moeten bij de dosering van medicijnen meer rekening houden met overgewicht. De verdeling in het lichaam en de afbraak van een geneesmiddel kunnen bij obese patiënten aanzienlijk afwijken. Dat stelt klinisch farmacoloog Catherijne Knibbe in Annual Review of Pharmacology and Toxic…
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Relatief meer patiënten naar brandwondencentra
Een steeds groter percentage slachtoffers met brandwonden gaat naar gespecialiseerde brandwondencentra. Dat blijkt uit onderzoek van Jan Dokter, brandwondenarts en medisch coördinator van het brandwondencentrum in het Maasstad Ziekenhuis te Rotterdam. Promotie op 20 december.
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Ewout Steyerberg
Faculteit Geneeskunde
e.w.steyerberg@lumc.nl | +31 71 526 9700