De afdeling Staats- en Bestuursrecht van de Universiteit Leiden heeft een bundel gepubliceerd over de vraag of de historisch gegroeide combinatie van de concepten van democratische legitimiteit en de scheiding van machten mogelijk blijft buiten de context van de traditionele staat, en indien dit mogelijk…

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Deelproject van “

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

Het voorgestelde project evalueert hoe de kwetsbaarheid van migrantenmannen en -vrouwen werd geconstrueerd in politieke, publieke en mediadiscoursen, en hoe verschillen in de geconstrueerde kwetsbaarheid van invloed waren op de beslissing om te migreren, het migratieproces en het daaropvolgende vest…

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

In June 2024, the University of Groningen organizes a summer school, titled "Things that Matter". The Summer School explores challenges in digitizing source materials, questioning distinctions between physical and digital copies. It delves into the impact of virtual collections and criteria for digitization,…

Promotor: Prof.dr. M. Ubbink

Presents a novel philosophical account of psychedelic experiences, arguing that they can be induced by means other than psychedelics — such as meditation and yoga.

Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

The applications of studying the early development of insects range from agriculture to material science.

In dit proefschrift wordt onderzocht welke kennis begeleiders van beginnende leraren hebben over adaptief begeleiden.

Het kiezen van de juiste studie is leuk en spannend, maar niet altijd makkelijk. Het is een belangrijke beslissing, het gaat tenslotte over je toekomst. Tegelijkertijd is het goed om je te realiseren dat het niet een keuze is voor de rest van je leven.

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

Veel leerlingen hebben problemen met het lezen van algebraische formules. Grafieken kunnen betekenis geven aan deze algebraische formules. Wat efficiënte methoden zijn om bij deze formules globale grafieken te maken is tot dusver onbekend.

Didactiek

Deelproject van

Op 1 juli 2020 verdedigde Niek Strohmaier zijn proefschrift 'Making Sense of Business Failure'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.A.A. Adriaanse en dr. H. Pluut.

Het vermogen om voorwerpen en bouwsels met de hand te maken, is essentieel geweest voor de ontwikkeling van de mens. De moderne samenleving dreigt dat vermogen te verliezen. Leidse archeologen verzamelen kennis over processen van ‘maken en creëren’ door de eeuwen heen. Die kennis helpt onze huidige…

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Deelproject van

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.

Planten zou je kunnen zien als kleine chemische fabrieken, die via fotosynthese chemische stoffen produceren. Als we fotosynthese kunnen nabootsen in een kunstmatig systeem, kunnen we schone brandstoffen en materialen maken uit zonlicht en CO2. Huub de Groot is heel dicht bij het ontwerpen van zo’n…

CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Organisaties als de EU leveren lidstaten soms enorm veel op, zonder dat inwoners van de lidstaten dat weten. Leidse wetenschappers onderzoeken hoe effectief samenwerkingsverbanden van lidstaten, zoals de EU of ASEAN, zijn bij het uitoefenen van invloed op de wereldpolitiek.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Promotor: H.V.J. Linnartz

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Promotor: Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Univ. de Bordeaux)