Overkleeft

Promotor: T. H. Oosterkamp

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

Nieuw onderzoek van de National University of Singapore en Leiden laat zien dat chimpansees en bonobo’s net zoveel contrast in hun ogen hebben als mensen, waardoor ze gemakkelijk de richting van iemands blik kunnen volgen.

Negentig jonge, pas gepromoveerde wetenschappers kunnen vanaf 1 februari reageren op een postdoc-positie binnen het LEaDing Fellows Postdocs Programma.

Prof. Vriesendorp en prof. Wessels zijn opgenomen in de 2020 Lawdragon 500 Leading Global Restructuring & Insolvency Lawyers. Prof. Haentjens is genoemd in de 2020 Lawdragon Leading Global Restructuring Advisors & Consultants.

De president van Indonesië, Susilo Bambang Yudhoyono heeft Jan Slikkerveer, hoogleraar Etnobotanische Kennissytemen in Ontwikkelingslanden, persoonlijk uitgenodigd om een lezing te houden op het World Culture Forum. Dat wordt van 24 tot 27 november in Indonesië gehouden.

Dit team zorgt ervoor dat alle Una Europa activiteiten soepel verlopen en biedt ondersteuning aan Leidse collega's die direct betrokken zijn bij Una Europa activiteiten.

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Cardiovascular disease is the leading cause of death worldwide.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment.

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

Galaxies form and live inside dark matter haloes. As a consequence, they are exposed to the tidal fields generated by the surrounding matter distribution: this imprints a preferential direction to the galaxy shapes, which leads to a coherent alignment on physically close galaxies, called intrinsic a…

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

The four possible segments A, T, C and G that link together to form DNA molecules, and with their ordering encode genetic information, are not only different in name, but also in their physical and chemical properties.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Prof.dr. J. Memelink

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Promotor: J.W. van Holten

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

Promotor: Prof.dr. J. Kuiper

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

Una Europa heeft zes transversale thema’s vastgesteld en ingevoerd als leidende beginselen voor samenwerking. Deze thema’s hebben als doel het personeel en de studenten van Una Europa te helpen deze thema's in concrete acties om te zetten.

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Healthcare robots and AI is een onderzoek naar juridische en reguleringsaspecten van robots en kunstmatige intelligentie in de zorg.

Het Leiden Leadership Centre is lid van de Global Leadership Centres Roundtable (GLCR). De Global Leadership Centres Roundtable is het internationale netwerk van universitaire leiderschapscentra.

Promotor: G.J.B. van Ommen

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

In 2015, CML published over 70 papers, contributed to the United Nations conference on climate change in Paris, won awards and advised the Dutch government on the safe use of pesticides. CML awarded 11 PhDs and taught students from all over the world how to contribute to sustainability. We wish you…

In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).

Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)

Some examples of research questions include: What framework of circular strategies should local practitioners use? How should practitioners organize their monitoring of the circular economy activities in the region of interest? What are the main products that have the most circular potential in the…

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

Cardiovascular diseases are still a major concern for the global health.

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.