The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

feestbundel voor de Britse demotisant Cary J. Martin (UC Londen)

Linde Desmaele onderzoekt de rol van Amerikaanse tactische kernwapens in Europa. Zij stelt dat deze wapens voornamelijk dienen als instrumenten voor bondgenootschapsbeheer.

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Promotores: F.H. van Lunteren, F.P. Israel

Promotores: J. Jonkers, K.E. de Visser

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

To study how planetary systems come into existence we study much younger systems still in formation.

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Effectiveness and Side-effects.

Cardiovascular diseases are still a major concern for the global health.

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.

Promotor: J. Schaye

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Promotor: Prof.dr. C.W.J. Beenakker

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Promotor: Prof.dr. G.P. van Wezel

Promotor: Prof.dr. E.F. van Dishoeck

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.

Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit

Promotor: P.D. Grünwald

The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…