598 zoekresultaten voor “gene theory” in de Publieke website
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
- Aflevering 12: The Selfish Gene
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Chromatin dynamics in single genes
Hoe beinvloed de structuur van één enkel gen de activiteit van genen die gevoelig zijn voor hormonen?
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Freedom of additional signals on genes: on the combination of DNA mechanics, genetics and translation speed
DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.
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Probability theory
Het onderzoeksprogramma Probability Theory richt zich op kansrekening en op operationeel onderzoek.
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Mersenne primes and class field theory
Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit
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Kummer theory for commutative algebraic groups
This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.
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Compressed Σ-Protocol Theory
In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.
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Modular curves, Arakelov theory, algorithmic applications
Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
- Aflevering 44: Theory of Mind
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Algebra, Geometry and Number Theory
Het onderzoek binnen het Algebra, Geometry and Number Theory programma varieert van fundamentele wiskundige theorie tot algoritmes en toepassingen.
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mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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On the random-matrix theory of Majorana fermions in topological superconductors
The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.
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Algebra, Geometry and Number Theory (MSc)
In de masterspecialisatie Algebra, Geometry and Number Theory verbreed je je kennis van de zuivere wiskunde met onderwerpen als getaltheorie, algebraïsche meetkunde, algebraïsche topologie en cryptologie.
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Cultural Analysis: Literature and Theory (MA)
De masteropleiding Cultural Analysis: Literature and Theory van de Universiteit Leiden richt zich op de studie van literatuur vanuit een vergelijkend en theoretisch perspectief, en onderzoekt de literatuur van een breed spectrum van talen en culturen uit de hele wereld.
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On cluster algebras and topological string theory
My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.
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Political Theory: Legitimacy and Justice (MSc)
In deze masterspecialisatie houd je je bezig met twee kernthema’s in de politieke filosofie: legitimiteit en rechtvaardigheid. Je verdiept je in theoriën, methoden en complexe casus en maakt de stap van opinie naar analyse.
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
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Deciphering fermionic matter: from holography to field theory
Promotor: K.E. Schalm, Co-promotor: S.S. Lee
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interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
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Online Course Terrorism & Counterterrorism: Comparing Theory & Practice
This six-weeks online course delves into the research behind terrorism as it unpacks the assumptions and impacts of both terrorism and counterterrorism.
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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Mechanisms and consequences of horizontal gene transfer in cell wall-deficient cells of Kitasatospora viridifaciens
The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…
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Many Babies 2: "Theory of mind"
In deze studie onderzoeken we of 2-3-jarigen in staat zijn te anticiperen op het gedrag van een personage door rekening te houden met wat dit personage wel of niet weet over de situatie. Het kind zit op schoot en krijgt animaties te zien met twee personages, waarbij de ene zich verstopt en de andere…
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analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice
Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang
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Gauge theory and nematic order : the rich landscape of orientational phase transition
Promotor: J. Zaanen
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Advances in computational methods for Quantum Field Theory calculations
In this work we describe three methods to improve the performance of Quantum Field Theory calculations.
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The Importance of Conspiracy Theory in Extremist Ideology and Propaganda
Op 16 april 2020 verdedigde Andrew Fink zijn proefschrift 'The Importance of Conspiracy Theory in Extremist Ideology and Propaganda'. Het promotieonderzoek is begeleid door promotor prof.dr. A. Ellian.
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Statistical physics and information theory for systems with local constraints
Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.
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Femke Bakker, Hawks and Doves: Democratic Peace Theory Revisited
Femke Bakker, Hawks and Doves: Democratic Peace Theory Revisited
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Novel approaches for direct exoplanet imaging: theory, simulations and experiments
The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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Applied String Theory: Explaining Quantum Matter with Black Holes
Hoe kunnen we de mysteries van quantummaterie verklaren?
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Boundary extensions of symmetric spaces in equivariant KK-theory
Promotie
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Terrorism and Counterterrorism Studies: Comparing Theory and Practice
Professor Edwin Bakker, directeur van het Centrum voor Terrorisme & Contraterrorisme heeft zijn nieuwe boek getiteld 'Terrorism and Counterterrorism Studies: Comparing Theory and Practice' bij Leiden University Press uitgebracht.
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Non-linear astrochemical kinetics: theory and applications
This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Nieuw Boek: Theory and Practice of Public Sector Reform
Het boek biedt verschillende theoretische perspectieven om het proces van publieke sector hervormingen te onderzoeken. Daarnaast geeft het een overzicht van de belangrijkste trends in publieke sector hervormingen in Europa en de Verenigde Staten.
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Geometric quadratic Chabauty and other topics in number theory
This thesis is is made of three parts. The first part describes a generalization of the Chabauty's method, that can be used to determine the rational points of a curve such that s+g>r+1, where g is the genusof the curve, r is the rank of the Mordell-Weil group of the jacobian of the curve and s is…
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Theory-enriched practical knowledge in mathematics teacher education
Het onderzoek gaat over de vraag op welke wijze en op welk niveau studenten van de opleiding voor leraar basisonderwijs theorie en praktijk kunnen integreren en hoe de inrichting van hun leeromgeving, toegespitst op het vak rekenen-wiskunde en didactiek, daaraan kan bijdragen.
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Cognitive enhancement: Toward the integration of theory and practice
Cognitive enhancement is het gebruik van elke methode of techniek met als doel het verbeteren van cognitieve prestaties.
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Exploring Justice in Extreme Cases: Criminal Law Theory and International Criminal Law
Op 12 mei 2020 verdedigde Darryl Robinson zijn proefschrift 'Exploring Justice in Extreme Cases: Criminal Law Theory and International Criminal Law'. Het promotieonderzoek is begeleid door promotor prof.dr. C. Stahn.
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is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.