Electron microscopy has become an extremely important techniquein a wide variety of elds.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

This thesis describes a study from both a theoreticaL and an experimental point of view.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Het doel van deze faciliteit is om het biomedisch onderzoek te versnellen door toegang te bieden tot geavanceerde licht- en elektronenmicroscopie en door het delen van expertise over monstervoorbereiding, beeldvormingsmodaliteiten, gegevensopslag en beeldanalyse.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

The dissertation describes TEM experiments on heterogeneous catalysts.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Promotores: G.W. Canters, T.J. Aartsma

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Ambtenarensystemen zijn wereldwijd krijgen wereldwijd veel kritiek. Dit artikel presenteert een onderzoek naar bewijsmateriaal over over overheidsprestaties en merictocratie.

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

By documenting lexical and morpho-syntactic patterns among P’urhepecha speakers in Mexico and the US diaspora, this project will investigate the sources of language variation. The ensuing online dialect atlas will serve as an online resource for speakers, learners and researchers of the language.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Op 1 december 2020 verdedigde Bernadette Muscat haar proefschrift 'Insolvency Close-out Netting: A comparative study of English, French and US laws in a global perspective'. Het promotieonderzoek is begeleid door promotoren prof.mr.drs. M. Haentjens en prof.mr. B. Wessels.

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Promotor: R. Gill, Co-promotor: P. Massart

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

De Young Academy Leiden verwelkomt maandag 20 september 6 nieuwe leden waaronder pedagoog Rachel Plak. Vanmiddag vindt er een de dubbele inauguratieceremonie plaats van deze leden én de leden die zich afgelopen jaar hebben aangesloten bij YAL. De ceremonie is van 17.00 uur tot 18.00 uur in het Academiegebouw…

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

De conferentie 'The

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Internationale experts van verschillende academische disciplines namen op vrijdag 8 en zaterdag 9 december 2017 te Leiden deel aan de internationale conferentie 'The

Onderzoeksgroepen in het Quantum Matter & Optics onderzoeksprogramma onderzoeken elektronische eigenschappen van interacties van materie en lichtmaterie, met de nadruk op quantuminformatie.

Natuurkundige Daniël Geelen ontwikkelde tijdens zijn promotie een nieuwe microscoop die laag-energetische elektronen gebruikt. Zulke elektronen zijn minder schadelijk voor biologische en organische materialen. Geelen promoveert op 31 mei.

Promotor: Prof.dr. J.W.M. Frenken

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Promotores: T.H. Oosterkamp, N. de Jonge

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee