1,273 zoekresultaten voor “for data” in de Publieke website
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Universal adelic groups for imaginary quadratic number fields and elliptic curves
Promotor: Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Univ. de Bordeaux)
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Suppressing a Sea of Starlight: Enabling technology for the direct imaging of exoplanets
Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik
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Lipid signaling and inflammation: metabolomics for better diagnosis and treatment strategy
Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…
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Are we there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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Development of automatic image analysis methods for high-throughput and high-content screening
Promotor: Prof.dr. B. van de Water
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Life Cycle Assessment-Based Guidance for development of New Energy Technologies
The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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The learning portfolio as a tool for stimulating reflection by student teachers
Het onderwerp van deze studie is het portfolio dat wordt gebruikt bij een lerarenopleiding als instrument om bij docenten in opleiding reflectie op hun ontwikkeling als docent te stimuleren.
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Computer interventions for young children at risk to prevent reading impairments
This study’s main aim is to test whether children’s learning behaviour explains why they do not benefit from a literate environment.
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Gisela Hirschmann, Coronavirus: A Global Crisis Waiting for a Global Response
Vaak wordt gezegd dat een crisis iemands ware aard naar boven brengt. Het coronavirus stelt het multilaterale systeem op de proef. Politicoloog Gisela Hirschmann (Universiteit Leiden) maakt zich zorgen over de toekomst van internationale samenwerking.
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Development of a academic monitoring system for students with learning problems in secondary school
Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years
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Capillary Electrophoresis-Mass Spectrometry based Metabolomics Approaches for Volume-restricted Applications
Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…
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The development of an assessment procedure for beginning teachers of English as a foreign language
Dit proefschrift beschrijft de ontwikkeling van een beoordelingsprocedure voor docenten, toegespitst op beginnende eerstegraads docenten Engels.
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'Biologen moeten ook een beetje data-analist zijn’
Het is tegenwoordig essentieel dat een bioloog om kan gaan met big data. Daarom moeten data-analysevaardigheden vanaf het begin van de studie, of liever zelfs vanaf de middelbare school, worden aangeleerd. Dat stelt Vera van Noort, de nieuwe hoogleraar Computationele Biologie. Oratie op 22 januari.
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'Data science kent geen grenzen'
Nederland heeft veel kennis in huis op het gebied van dataonderzoek. Dat zeggen de Leidse hoogleraren Joost Kok en Aske Plaat op 21 augustus in NRC Handelsblad. Ze reageren daarmee op een interview met hoogleraar Wil van der Aalst. Lees hier de uitgebreide versie van hun betoog.
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SAFE and SOUND: Towards Evidence-based Policies for Safe and Sound Robots
SAFEandSOUND heeft de ambitie om de beleidscyclus te verbinden met gegevens die zijn gegenereerd in robottestzones om empirisch onderbouwde beleidsvorming voor robottechnologieën te ondersteunen.
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Shaping multilateralism: Principles and opportunities for multilateral cooperation in the UN
Hoe kan internationale samenwerking worden bevorderd, nu de steun voor de mulilaterale aanpak van problemen afkalft? Gisela Hirschmann (Universiteit Leiden) en Cornelia Ulbert (Universiteit van Duisburg-Essen) doen enkele aanbevelingen.
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Delegation to Treaty Bodies and International Organisations for Conventional Arms Control Agreements in Europe
In dit artikel onderzoekt William Lippert hoe het overdragen van taken aan een uitvoerder van een overeenkomst van conventionele wapenbeheersing in Europa van invloed is op het succes ervan.
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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reforms practical for teachers: using a modular, success-oriented approach to make a context-based educational reform practical for implementatiion
Docenten spelen een cruciale rol bij het implementeren van onderwijsvernieuwingen. Uiteindelijk hangt het succes van de implementatie af van de manier waarop docenten de vernieuwing vormgeven in hun dagelijkse lespraktijk.
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Imaging polarimetry for the characterisation of exoplanets and protoplanetary discs. Scientific and technical challenges
Promotor: Prof.dr. C.U. Keller
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Construction and exploration of modular goldnanoparticles for glycan-based immune-interventions of worm infections
Chiodo
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SDS-PAGE at the nanoscale: A nanorecorder for single molecule protein sequencing with graphene
Schneider
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Framing international cooperation: citizen support for cooperation with the European Union in Eastern Europe
This article studies the influence of framing on preferences for cooperation with the EU.
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A solid start for the Dutch first thousand days-approach
Promotie
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Ariane Briegel
Wiskunde en Natuurwetenschappen
a.briegel@biology.leidenuniv.nl | +31 71 527 8850
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Moeten techreuzen verplicht data delen?
Grote techbedrijven, zoals Google, Facebook en Apple, moeten verplicht hun data delen met nieuwkomers en concurrenten. Hiervoor pleiten wetenschappers en onderzoeksbureau TNO in een hoorzitting in Tweede Kamer. Tom Ottervanger verwacht dat het heel lastig gaat worden om dit te verplichten.
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Material flow analysis for the C&D waste management systems in the Netherlands, Belgium, Spain and Finland
What are the flows of C&DW (e.g. bricks, concrete, gypsum and wood) in the case study countries ? How to define the specification for each material to be quantified? What indicators should be used to identify the pattern of each C&DW management system? How to interpret the MFA results in relation…
- Het Common European Framework of Reference for Languages
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Biological indicators for sustainable forest management, East Kalimantan, Indonesia. The impossible made possible?
What is vegetation structure and composition in SFM primary forest, secondary logged over forest (logging FSC certified and logging non certified) in comparison to primary forest? What is avian guild diversity in SFM primary forest, secondary logged over forest (logging FSC certified and logging non…
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Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects
Op 20 oktober 2021 verdedigde Michael Ramsden het proefschrift 'The Role of the United Nations General Assembly in Advancing Accountability for Atrocity Crimes: Legal Powers and Effects'. Het promotieonderzoek is begeleid door promotor prof.dr. N.M. Blokker.
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Max van Haastrecht
Wiskunde en Natuurwetenschappen
m.a.n.van.haastrecht@liacs.leidenuniv.nl | +31 71 527 4799
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Wouter van Loon
Faculteit der Sociale Wetenschappen
w.s.van.loon@fsw.leidenuniv.nl | +31 71 527 2727
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Fertility and fontanels: women’s knowledge of medicinal plants for reproductive health and childcare in western Africa
Promotor: E.F. Smets, Co-promotor: T.R. van Andel
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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Metastability for low-temperature Kawasaki dynamics with two types of particles
Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Management implications for invertebrate assemblages in the Midwest American agricultural landscape
Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters
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G-zips and Ekedahl-Oort strata for Hodge type Shimura varieties
Promotores: S.J. Edixhoven, F. Andreatta
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in urinary tract infection: definitions, diagnostics, and strategies for prevention
Promotie
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Metabolomics- and methylomics-based predictors for estimating health and biological aging
Promotie
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Embracing a new beginning: understanding the teachable window for lifestyle change
Promotie
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia
Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.