Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Galaxies in the Universe are distributed along the intricate framework of the Cosmic Web. Groups and clusters of galaxies comprise the densest regions in this network, and therefore, are excellent cosmic laboratories to study different aspects of galaxy evolution in extreme environments.

In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

Geometric phases lead to a nontrivial interference result when an electron's different quantum mechanical paths choices encircle a magnetic coil in an Aharonov-Bohm experiment.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Promotores: G. Persoon, R. Schefold

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

Artificiele Intelligentie en Ethiek bij de Politie

Een systematische literatuurstudie naar de intergenerationele overdracht van extremistische denkbeelden binnen de gezinscontext.

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotor: J. Aarts

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

De afdeling Environmental Biology (CML-EB) houdt zich bezig met vraagstukken rondom biodiversiteit en natuurlijke hulpbronnen op het platteland in westerse en niet-westerse gebieden.

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Een wetenschappelijk onderzoek naar de versterking van de verantwoordelijkheid van gecontroleerde entiteiten zelf rondom de accountantscontrole en de jaarverslaggeving.

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Persvrijheid in Indonesië staat nog steeds onder druk, ondanks de val van Soeharto’s regime in 1998.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

My work focuses on a class of astronomical objects called protoplanetary disks.

Mensen die de afgelopen drie maanden antibiotica hebben gebruikt, letten meer op negatieve gezichtsuitdrukkingen, blijkt uit onderzoek van postdoc Katerina Johnson en universitair docent Laura Steenbergen. Dit kan mogelijk verklaren hoe antibiotica het risico op het ontwikkelen van depressie vergroo…

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

Hoe kun je virussen als medicijn laten werken? Hoe kunnen bacteriën schadelijke stoffen in het milieu afbreken? Hoe worden algen omgevormd tot producenten van biobrandstof? Dit zijn typische vragen die je bij de opleiding Life Science & Technology behandeld. Je leert doorgronden hoe de cel is opgebouwd…

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Hoe kun je virussen als medicijn laten werken? Hoe kunnen bacteriën schadelijke stoffen in het milieu afbreken? Hoe worden algen omgevormd tot producenten van biobrandstof? Dit zijn typische vragen die je bij de opleiding Life Science & Technology behandeld. Je leert doorgronden hoe de cel is opgebouwd…

Het beste van Leiden en Delft komt samen in de bachelor opleiding Life Science & Technology. Benieuwd naar het programma? Bekijk de video.

Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Met een masterdiploma op zak heb je meer kans op een baan op academisch niveau. Na afronding krijg je de titel Master of Arts (MA).

De Engelstalige master Biomedical Sciences in Leiden gaat over het bestuderen van normale en abnormale processen in het menselijk lichaam. Zo leer je ziektes beter te begrijpen, bestaande therapieën te verbeteren of nieuwe therapieën te bedenken. Naast het algemene programma dat zich toespitst op het…

De internationale machtsverhoudingen veranderen ingrijpend volgens Rob de Wijk hij vertelt over een nieuwe wereldorde bij 'De Ongelooflijke Podcast'.

Things that Matter: Material and Culture in/for the Digital Age. Bern, 23-27 June 2025.

Op woensdag 2 november 2016 vond op initiatief van de Universiteit Leiden en de Rijksuniversiteit Groningen een expertmeeting over ‘het honours als proeftuin’ plaats. Coördinatoren, beleidsmedewerkers en docenten die werkzaam zijn in het honoursonderwijs van verschillende hbo en wo instellingen kwamen…

Promotie