1,725 zoekresultaten voor “role work in range environmental” in de Publieke website
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Looking Beyond Our Similarities
How Perceived (In)Visible Dissimilarity Relates to Feelings of Inclusion at Work
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Onderwerp: Placebo
De effecten van veel behandelingen worden in belangrijke mate bepaald door andere factoren dan het geneesmiddel of de behandeling zelf. Zo kunnen placebo-effecten even groot zijn als het effect van bijvoorbeeld antidepressiva of pijnstillers. Factoren die hieraan bijdragen zijn het vertrouwen in de…
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Ethan Mark
Grensverleggend geschiedenis leren.
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Flows of six heavy metals
Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Eerste West-Europese ScienceOnline-community start in Leiden
In Leiden gaat op 30 mei de eerste ScienceOnline-community in West-Europa van start. ScienceOnline is een nieuwe community voor wetenschap en online communicatie.
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Diploma uitreiking MIRD 2021
Op vrijdag 9 juli 2021 vond de diploma-uitreiking plaats van het tweejarig programma MSc International Relations and Diplomacy (Advanced). De ceremonie werd geopend door Prof. Madeleine Hosli.
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Smart Industrial Parks in China: towards Joint Design and Institutionalization
How to contribute to a quantum leap of eco-industrial symbiosis in China?
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Transfusion Medicine and Cellular and Tissue Therapies (MSc)
This joint Master with the Autonomous University of Barcelona will the equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. The programme includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy, and…
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Public lecture: 'The ocean’s role in mitigating climate change'
Lezing
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Evaluatie en implementatie van innovatieve diagnostiek en behandelingen
Als een nieuwe methode is ontwikkeld om een (neuro-)psychologische aandoening of hieraan gerelateerde gedragsfactoren te herkennen en te behandelen, kan deze nog niet direct in de klinische praktijk worden ingezet. Eerst moet de methode geëvalueerd worden, bij voorkeur in gerandomiseerde, gecontroleerde…
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Internship information
An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.
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Armin Cuyvers
Van onderwijs tot een verrijkende ervaring
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EXIOBASE
EXIOBASE is a global, detailed Multi-regional Environmentally Extended Supply and Use / Input Output (MR EE SUT/IOT) database. It was developed by harmonizing and detailing SUT for a large number of countries, estimating emissions and resource extractions by industry, linking the country EE SUT via…
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Jaarverslag CML 2013 - 2014 (English)
In 2013-2014, CML published over 100 papers, contributed to various international sustainability debates, renovated our building and educated thousands of students from all over the world through our MOOC. These accomplishments and many more are highlighted in this booklet, CML wish you a pleasant…
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SFA of PVC in Sweden
In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).
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Multifaceted role of the complement system in health and disease
Promotie
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Role of intestinal microbiota in cardio-metabolic disease
Promotie
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Seeing voices: the role of multimodal cues in vocal learning
Promotie
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Online Course International Law in Action: The Arbitration of International Disputes
This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…
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Online Course International Law in Action: A Guide to the International Courts and Tribunals in The Hague
This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.
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Wat is beter voor het milieu, kleding van katoen of polyester?
Welke kleding kun je het beste kopen als je aan het milieu wilt denken? Die vraag is nog niet zo makkelijk te beantwoorden. Je moet namelijk rekening houden met de hele levenscyclus van een kledingstuk: van productie tot het moment dat we het de deur uit doen. In de rubriek 'What's better?' van radioprogramma…
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Onderzoek
Steden, Voedsel, Water, Biodiversiteit, Bronnen en Energie: dit zijn de belangrijkste onderzoeksthema’s voor het CML. Ons doel is altijd om wereldwijd voorop te lopen in ons vakgebied. En echte impact te hebben met onze onderzoeksprogramma’s.
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Monitoring and detection of nanomaterials in biological media.
How do nanoparticles bioaccumulate and biodistribute in organisms?
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Publicaties
Hieronder vind je een overzicht van de publicaties van LAPP.
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Dynamical Gibbs-non-Gibbs transitions: a study via coupling and large deviations
Promotores: F.H.J. Redig, W.T.F. den Hollander
- Alumini
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Assistant Professor Crisis Governance (1 fte)
Governance and Global Affairs, Institute of Security and Global Affairs
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Dissonance: How new digital technologies are changing professional roles in contemporary newsrooms
Promotie
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Career College: Working as a Data Scientist
Loopbaan en solliciteren
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Robert Verpoorte
Wiskunde en Natuurwetenschappen
verpoort@chem.leidenuniv.nl | +31 71 527 4528
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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The puzzle of protoplanetary disk masses
My work focuses on a class of astronomical objects called protoplanetary disks.
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Adding fuel to the conflict : how gas reserves complicate the Cyprus question
In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Structure dependence of molecular reactions on surfaces
The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.
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Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.