Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

De opleiding Life Science and Technology (LST) stond 9 september 2014 met een feestelijk gebakje stil bij haar 15 jarig bestaan. Het gaat bijzonder goed met de opleiding. Er zijn veel eerstejaars studenten en LST masterstudenten vinden of vóór hun diploma-uitreiking of er vlak na een goede baan.

Het Centre for Digital Scholarship van de Universitaire Bibliotheken Leiden (UBL) en het Leiden Centre for Digital Humanities nodigen u graag uit voor het symposium over Tools Criticism op donderdag 21 november van 10.00-18.00 uur. Het symposium wordt gehouden in de Vossiuszaal van de Universiteitsbibliotheek,…

Promotie

Promotie

Ruim drie miljoen euro heeft hoogleraar Hilde De Weerdt de komende jaren te besteden. Voor onderzoek naar Chinese infrastructuur krijgt ze zowel subsidie van de European Research Council (ERC) als van de Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO). ‘Het is mooi dat het ook in de sociale…

Lezing

Lezing

In dit artikel presenteren Andrea Bartolucci en Michele Magni een evidence-based onderzoek naar de spontane opname van slachtoffers en de verdeling van patiënten in de onmiddellijke nasleep van de Manchester Arena Bombing.

Promotie

Promotie

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotie

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

Promotor: Prof.dr. H.S. Overkleeft

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

Promotor: Bas Edixhoven, Promotor: Qing Liu

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

This thesis attempts to interrogate post-1991-2015 political development in Ethiopia, focusing on the political discourses espoused by the government and opposition, using the discourse analysis method and securitization theory.

In this dissertation, matching, entropy, holes and expansions come together. The first chapter is an introduction to ergodic theory and dynamical systems.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets