1,330 zoekresultaten voor “group and robin history” in de Publieke website
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The alignment of galaxies across all scales
Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.
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Design, synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
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The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Klinische kennis in kaart gebracht. Het gebruik van concept maps om klinische kennis en kennis van de basisvakken te integreren
Hoe en in welke mate kunnen groepen clinici en biomedici kennis uit klinische vakken en kennis uit de basisvakken expliciet maken en aan elkaar relateren?
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Integrative taxonomy of araneomorph spiders: Breathing new life into an old science
Taxonomy as a science has accumulated data and knowledge for more than 250 years.
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A monograph of the plant genus Trigonostemon Blume
Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.
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Computational electrocatalysis
This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
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Cosmic tomography with weak gravitational lensing
We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water
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Zipping into Fusion
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Modular curves, Arakelov theory, algorithmic applications
Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong
- Praktische informatie
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)
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Beschadigd vertrouwen
Op 7 december 2021 verdedigde Georgina Kuipers het proefschrift 'Beschadigd vertrouwen'. Het promotieonderzoek is begeleid door prof.mr. W. den Ouden en prof.dr. M.A. van der Steen (EUR).
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Terreur en legitimatie van geweld: een transnationale analyse van de relatie tussen terrorisme en moorden
Dit artikel geschreven door Marieke Liem & Alexander Kamprad onderzoekt de relatie tussen terrorisme en interpersoonlijk geweld. Ze voerden cross-nationale analyses uit over de effecten van mortaliteitscijfers voor het terrorisme op moordcijfers. Uit de resultaten bleek dat terrorisme sterk en positief…
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Aspects of Record Linkage
Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft
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Picturing Intimacy: Mediation and Self-representation in a Boston’s Religious Festivals
Taking as a point of departure the Italian American community in Boston and its process of collective remembrance surrounding Saint Anthony’s Feast, we addressing the limits and potential of montage.
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Contributions to the phylogeny of the haplolepideous mosses
The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…
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Data Driven Modeling & Optimization of Industrial Processes
Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Counting points on K3 surfaces and other arithmetic-geometric objects
This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Reactivity and Selectivity in Glycosylation Reactions
The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Studying dark matter using weak gravitational lensing : from galaxies to the cosmic web
Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
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Ladies-only! Empowerment and Comfort in Gender-segregated Kickboxing in the Netherlands
The experiences of ethnic ‘Other’ females have – until recently – been widely overlooked in the study of sport. There continues to be a need to produce critical scholarship about ethnic 'Other' girls and women in sport and physical culture, in order to represent their complex, multifarious and dynamic…
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Eregalerij
Ontdek de uitzonderlijke prestaties en bijdragen van onze academici en onderzoekers, die nationale en internationale erkenning hebben ontvangen voor hun werk in diverse geesteswetenschappelijke disciplines. Leer meer over hun invloedrijke onderzoek en impact binnen de academische gemeenschap en daar…
- Kaiser Lente Lezingen: Launching into the night — a brief history of space exploration
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Gert Oostindie geeft lezing over koloniaal verleden
Oktober is de Maand van de Geschiedenis, die in 2016 draait om het thema Grenzen. Tijdens het Geschiedenisfestival op 8 oktober geeft Gert Oostindie een snelcollege koloniale geschiedenis.
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ERC Starting Grant voor prof.dr. Remco Breuker
Hoogleraar Koreastudies Remco Breuker onderzoekt dankzij deze subsidie van de European Research Council hoe beide Korea’s en China strijden om het oude Mantsjoerije.
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Why is there no Northeast Asian security architecture?
Waarom is er geen Noordoost Aziatische veiligheidsstructuur? In dit artikel, gepubliceerd in The Pacific Review, bespreken auteurs Wang (Peking University) en Stevens (Leiden University) de vier obstakels voor coöperatie in Oost Azië.
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2012 Even voorstellen: Lotte Pelckmans
Lotte Pelckmans is op 1 november 2012 aan ons Instituut begonnen met een postdoctoraal onderzoek.
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Microfluidic 3D cell culture for high throughput screening
There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Brieven als buit
Alledaagse taal uit het verleden kennen wij nauwelijks, maar taalkundig onderzoek van een unieke brievencollectie opent perspectieven. Buitgemaakte brieven van mannen, vrouwen en zelfs kinderen stonden centraal in het Leidse Brieven als Buit-project onder leiding van prof. dr. Marijke van der Wal, dat…
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Onderwijs
Leids rechtshistorisch onderwijs
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PhD Historisch onderzoek eenzaamheid en handicap
Geesteswetenschappen, Instituut voor Geschiedenis
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Lobbyende burgers hadden veel invloed in de Gouden Eeuw
Door fanatiek te lobbyen hadden uiteenlopende groepen burgers en handelaren een grote invloed op het aanvankelijke succes van de Nederlandse kolonie in Brazilië. Dat constateert de Leidse promovendus Joris van den Tol. Promotie op 20 maart.