Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

Het Europaeum is een netwerk van 17 vooraanstaande Europese universiteiten, met als doel om talentvolle studenten en docenten met elkaar in contract te brengen en door samenwerking en academische mobiliteit een 'Europees gevoel' te bevorderen.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Promotor: Prof.dr. F. den Hollander, G.Maillard

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.

Promotor: V. Vitelli, Co-promotor: J. Paulose

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotores: Bas Edixhoven, Guy Henniart

Programma's die de symptomen van sociale angst bij kinderen willen verminderen, omvatten doorgaans meerdere onderdelen, zoals blootstelling en mentale herstructurering. Het is onbekend of afzonderlijke onderdelen positieve effecten opleveren bij kinderen of dat een combinatie van onderdelen nodig is…

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Promotores: P. Stevenhagen, A. Enge Co-Promotor: T.C. Streng

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Promotor: Prof.dr. C.W.J. Beenakker

Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

Promotor: Prof.dr. M.L. van Hecke

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

Het Instituut Politieke Wetenschap blijft graag in contact met alumni. Van onze afstudeerders kunnen wij veel leren. En we helpen natuurlijk ook graag een handje om ‘onze’ politicologen in binnen- en buitenland met elkaar te verbinden.

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Make use of this time to improve your language skills by signing up for custom-made online language classes.

De Academy of Creative and Performing Arts is een samenwerkingsverband tussen de Leidse universiteit en de Hogeschool der Kunsten Den Haag'. (Deeltijd)studenten van de Leidse universiteit kunnen hier theoretisch en praktisch kunstvakonderwijs volgen, waarvan de studiepunten meetellen voor hun bachelor-…

Kunst en vrije tijd, Kunst en vrije tijd

De Oorlog in Oekraïne is ook een informatie-oorlog, en met name Britse en Amerikaanse inlichtingendiensten spelen daarin een belangrijke rol. Zij delen dagelijks informatie over de Russische plannen en troepenbewegingen. Willemijn Aerdts, docent bij ISGA, vertelt erover op NPO Radio 1.

Oekraïne daagde met een innovatieve claim Rusland voor het Internationaal Gerechtshof (IGH). Oekraïne vroeg het Hof vast te stellen dat het geen genocide had gepleegd, en voorts om te bepalen dat een oorlog begonnen op basis van een valse genocide-claim onrechtmatig was. Larissa van den Herik, hoogleraar…

De aanmeldprocedure bestaat uit vier delen.