In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Promotor: W. Jiskoot, Co-promotor: A. Kros

This thesis concerns the relation bettween the good reduction of Shimura varieties and the associated loop groups.

This thesis focuses on the role of chemokine receptors CXCR3 and CCR2 in the inflammatory process and infection control using the zebrafish model.

Promotor: S.J. Edixhoven

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Promotor: Prof.dr. G.P. van Wezel

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.

The main theme of this thesis is the theoretical study of Gaussian processes as a tool in Bayesian nonparametric statistics.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Promotor: Prof.dr. J.P. Abrahams

A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.

Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood

Promotor: Prof.dr. P. Stevenhagen, Jan-Hendrik Evertse, Co-promotor: Pascal Autissier

This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

We investigate how radiation pressure can be used to influence the mechanical motion of a micro-mirror suspended from springs.

Promotor: F.S. de Boer Co-promotor: P. T. de Gouw

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

Promotor: Prof.dr. M. Ubbink

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

In our research protein translocation from Agrobacterium into yeast and plant cells is studied to obtain fundamental insights in the translocation process

The focus of this thesis is on the technical methods which help promote the movement towards Trustworthy AI, specifically within the Inspectorate of the Netherlands.

In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

An algorithm is discussed to compute the exponential representation of principal units in a finite extension field F of the p-adic rationals.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)

Promotor: B. van de Water, Co-promotor: E.H.J. Danen

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Promotor: S.J. Edixhoven, L.D.J. Taelman

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

This thesis is about cosmological inflation and its relation to observations.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Promotor: J.M. Memelink