Sustainable energy from wind and solar is most readily available near the sea.

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

In this thesis we push the boundaries of high-resolution imaging at radio frequencies between 100 and 200 MHz. Using the International LOFAR Telescope that spans across Europe we achieve sub-arcsecond angular resolution.

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

The class-imbalance problem is a challenging classification task and is frequently encountered in real-world applications. Various techniques have been developed to improve the imbalanced classification performance theoretically and practically.

Timo Slootweg, associate professor at he department Philosophy of Law, published a chapter about Paul Scholten in

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

Rechtsgeleerdheid, Instituut voor Metajuridica, Van Vollenhoven Instituut

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

Promotor: Prof.dr. J.W.M. Frenken

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Prof.dr. J. Memelink

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

The experiences of ethnic ‘Other’ females have – until recently – been widely overlooked in the study of sport. There continues to be a need to produce critical scholarship about ethnic 'Other' girls and women in sport and physical culture, in order to represent their complex, multifarious and dynamic…

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

This thesis aims to address offshore wind energy (OWE)-related environmental impacts.

In een paar jaar tijd is het beleid van de Chinese regering ten opzichte van de Oeigoeren sterk verslechterd. Van controle en marginalisering ging het naar een schending van mensenrechten. Promovenda Elke Spiessens zat er met haar onderzoek middenin. ‘De vezels van de gemeenschap worden volledig weg…

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.

During the course of drug discovery translational steps are made.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Promotor: C.J. ten Cate

Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Bij Cambridge University Press (CUP) verscheen onlangs van Ingrid Leijten het boek Core Socio-Economic Rights and the European Court of Human Rights. Het boek maakt onderdeel uit van de serie Cambridge Studies in European Law and Policy en heeft als onderwerp de bescherming van sociaaleconomische rechten…

This initiative is intended to support generative research collaborations between and among scholars located in different geographical regions who wish to pursue focused, joint projects in any area of the study of religion.

Promotor: G.P. van Wezel

Promotor: J. Kuiper

Promotor: J. Zaanen

Including modelling as part of software development appears to have various benefits.

Indonesië is deze dagen de achtergrond van de G20-top. Een uitgelezen kans voor het land om zich als zelfbewust te profileren. In de Volkskrant gaat hoogleraar David Henley in op de Indonesische ambitie om in 2045 een hooginkomensland te zijn.