267 zoekresultaten voor “etnische profiling” in de Publieke website
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Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
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The evolution of shell form in tropical terrestrial microsnails
Promotor: Prof.dr. M. Schilthuizen
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Biodiesel production using blue-green cyanobacterium Synechococcus elongatus PCC 7942
Promotores: Prof.dr. C.A.M.J.J. van den Hondel, Prof.dr. V. Meyer (Technische Universität Berlin)
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Diversiteit in de culturele sector
In opdracht van het Nationaal Museum van Wereldculturen in samenwerking met de Boekmanstichting onderzochten Anouk de Koning en Jasmijn Rana de huidige manieren van meten en monitoren van (etnoraciale) diversiteit binnen culturele instellingen. In de publicatie Diversiteit in de culturele sector: een…
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Identity, Ethnicity and Political Community
Binnen het onderzoeksprogramma ‘Institutions, Decisions and Collective Behaviour’ richt het onderzoekscluster ‘Identity, Ethnicity and Political Community’ zich op vraagstukken rondom identiteit en diversiteit. De betrokken onderzoekers bestuderen zaken als migratie, immigratie, burgerschap, integratie,…
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Nationalism, Ethnic Conflict and Development (MSc)
Het organiseren van diversiteit is een van de grootste uitdagingen van nu. Etnische, raciale, religieuze en culturele verschillen staan wereldwijd op de agenda, dikwijls omdat deze leiden tot gewelddadige conflicten. In deze masterspecialisatie kijk je waarom en hoe deze conflicten ontstaan en welke…
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Masterclass Inclusieve Communicatie
Inclusieve communicatie is van essentieel belang in een diverse samenleving. In een maatschappij waarin mensen van verschillende achtergronden, culturen en capaciteiten samenkomen, is het essentieel om communicatie te omarmen waarbij iedereen wordt gezien. Inclusieve communicatie gaat verder dan het…
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Bart Custers geeft big data keynote lezing in Japan
Op 23 oktober 2017 geeft mr.dr.ir. Bart Custers, hoofd onderzoek bij eLaw, het centrum voor recht en digitale technologie van de Universiteit Leiden, een keynote lecture over big data en recht op de International Conference on Big Data Research (ICBDR 2017) in Osaka, Japan.
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Burgerschap: gevolgen van democratisering
Veel Aziatische landen maken een democratiseringsproces door. De verwachting was dat burgers langzaam meer controle over het functioneren van hun elites zouden krijgen. Leidse experts concluderen dat dit proces de kwaliteit van het bestuur vaak niet verbetert. Ze onderzoeken het karakter van burgerschap…
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Access Q&A, explaining different options based on four researcher profiles
Lezing
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Structure and substructure in the stellar halo of the Milky Way
Promotor: K.H. Kuijken
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Microcoil MRI of Plants and Algae at Ultra-High Field: An exploration of metabolic imaging
This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
- Hedendaags Latijns-Amerika: cultuur, politiek en maatschappij
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Wetenschappelijke publicaties
Een lijst met wetenschappelijke publicaties samengesteld door het team van het TRIXY Expertisecentrum.
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Bart Custers
Faculteit Rechtsgeleerdheid
b.h.m.custers@law.leidenuniv.nl | +31 71 527 8838
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The ecological relevance of chemical diversity in plants
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Leukemia treatment & cognitive development
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Systems pharmacokinetic models to the prediction of local CNS drug concentrations in human
Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.
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Travelling waves on trees and square lattices
In this thesis we study bistable reaction-diffusion equations on lattice domains.
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The structure of the dusty cores of active galactic nuclei
Promotor: W. Jaffe, Co-promotor: K. Meisenheimer
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Ingredients of the planet-formation puzzle
High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Estimation and Optimization of the Performance of Polyhedral Process Networks
Promotor: Prof.dr.ir. E. Deprettere
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Metabolomic characteristics of Catharanthus roseus plants in time and space
Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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Surface plasmon lasers
Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Using soil inoculations for ecological restorations
How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Discovery of selective diacylglycerol lipase β inhibitors
Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…
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Samenwerking
Voor de ontwikkeling, de impact en de kwaliteit van onderwijs en onderzoek zijn intensieve verbindingen met in (de regio van) Den haag gevestigde organisaties van groot belang.
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Anti-Joodse beeldvorming en Jodenhaat
Van alle vormen van etnisch en raciaal vooroordeel heeft het antisemitisme verreweg de langste geschiedenis. In zijn nieuwe boek analyseert Chris Quispel het anti-semitisme over vijfentwintig eeuwen.
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Gender in ethnically mixed relationships of immigrants from Dutch former colonies in the Netherlands, 1945-2005
Deelproject van
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Kenniswerkplaats Diversiteit voor het Onderwijs in Den Haag. Een samenwerking tussen gemeente, voortgezet onderwijs, hogescholen en universiteiten
Een kenniswerkplaats is een samenwerkingsverband tussen verschillende organisaties, zoals scholen, onderzoeksinstellingen en beleidsmakers. Het doel is om gezamenlijk praktijkgericht onderzoek uit te voeren om kennis te ontwikkelen en beschikbaar te maken voor de praktijk.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.