Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotor: M.A.G.J. Orrit

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotor: Prof.dr. J. Kuiper

Promotor: Prof.dr. B. van de Water

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Op 7 december 2021 verdedigde Georgina Kuipers het proefschrift 'Beschadigd vertrouwen'. Het promotieonderzoek is begeleid door prof.mr. W. den Ouden en prof.dr. M.A. van der Steen (EUR).

Promotor: T. H. Oosterkamp

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotores: W. Jiskoot, F. Ossendorp

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

Promotores: T.H. Oosterkamp, N. de Jonge

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: Prof.dr. G.J. Kroes

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Promotores: G.A. Persoon, H.H. de Iongh

In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…

Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Natural resources often stretch across borders that separate modern nation states. This can create conflict and limit opportunities for regulated consumption of their goods and services, but also provide opportunities for joint multinational efforts that exceed single country capabilities.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.

Op 23 april verdedigde Rowie Stolk het proefschrift 'Procederende belangenorganisaties in de polder: een interdisciplinair perspectief op de toegang tot de rechter'. Het promotieonderzoek is begeleid door Ymre Schuurmans en Jerfi Uzman.

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Bij Cambridge University Press (CUP) verscheen onlangs van Ingrid Leijten het boek Core Socio-Economic Rights and the European Court of Human Rights. Het boek maakt onderdeel uit van de serie Cambridge Studies in European Law and Policy en heeft als onderwerp de bescherming van sociaaleconomische rechten…