There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

This thesis focuses on addressing four research problems in designing embedded streaming systems.

Description of Triple bottom line approach for risk-benefit analysis of genetically modified crops.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

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Fokelien Kootstra verdedigde haar proefschrift op 23 april 2019

This study seeks to analyse how job stress could be the result of performing administrative tasks

Dit artikel beoordeelt de Russische retoriek ten aanzien van Oekraïne door verklaringen van het Russische ministerie van Buitenlandse Zaken te analyseren.

Op 27 september promoveert Josephine Hartmann op haar proefschrift: A blessing in disguise?! Discretion in the context of EU decision-making, national transposition and legitimacy regarding EU directives.

Hoe moet de EU omgaan met Oekraïne, Wit-Rusland en Moldavië? Hoe kunnen we de Europese Unie helpen om, in een uiterst moeilijke en veeleisende geopolitieke context, zijn politiek ten aanzien van deze landen te heroverwegen?

Promotie

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

Indonesia is experiencing various environmental challenges related to its fast economic growth. Therefore, it is necessary to have measurable and applicable indicators to obtain accurate data and information regarding the costs of adverse environmental impacts arising from economic activities to support…

What are trait-trait relationships in wetlands? To what extent the so-called leaf economics traits deviate from terrestrial ecosystems? How traits specific to wetland plant relate to plant strategies? What’s the relationship between wetland plant traits to the ecosystem functioning (e.g. productivity,…

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

Op 5 september 2019 verdedigde Jennifer Doekhie haar proefschrift 'Dimensions of desistance: A qualitative longitudinal analysis of different dimensions of the desistance process among long-term prisoners in the Netherlands'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Nieuwbeerta.

Survival Analysis for Junior Researchers 2018 werd georganiseerd in Leiden.

The global agri-food system plays a critical role in food security and environmental issues.

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

Promotor: W.T. de Groot

Prof.dr. J. Memelink

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Promotie

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

How to ensure the environmental and economic benefits of circularity transition at macro-scale?

Sinds april 2019 heeft de Faculteit der Sociale Wetenschappen er een nieuwe locatie bij voor haar onderzoek. Het Levelgebouw (direct naast Leiden Centraal) ontvangt proefpersonen in 3 gloednieuwe laboratoria. Psycholoog Carsten de Dreu vertelt enthousiast over de nieuwe mogelijkheden voor zijn onder…

Promotor: Prof.dr. B.R. Katzy

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

Yvonne Erkens en Fieke Weber, beiden werkzaam bij de Afdeling Sociaal Recht hebben onlangs namens het journal ILaRC een panel georganiseerd tijdens het ISLSSL World Congres in Rome. Dit panel, getiteld ‘Landmark Decisions on Fundamental Labour Standards: A Decade of Impact’, werd georganiseerd ter ere…

Sinds 2013 voegen landen gemakkelijker namen toe aan de Amerikaanse terrorismelijst (TSDB), vertelt Jelle van Buuren in De Telegraaf.

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

A new environmental accounting framework using externality data and input-output tools for policy analysis.

Promotor: Prof.dr. G.P. van Wezel