Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

In 2013-2014, CML published over 100 papers, contributed to various international sustainability debates, renovated our building and educated thousands of students from all over the world through our MOOC. These accomplishments and many more are highlighted in this booklet, CML wish you a pleasant…

How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

Do Ethiopian wolves change their diet and foraging strategy in the landscape under different land uses? How land use affect Afro-alpine rodent Communities? How important are Afro-alpine natural resources utilisation for local livelihoods? What is the human perception of conflict in the Afro-alpine a…

Hoe kan de methode om de gecombineerde effecten van metaal-gebaseerde chemische stoffetn te bepalen worden verbeterd?

Promotor: G.R. de Snoo, Co-promotores: M.G. Vijver, J.P.M. Vink

The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds.

Promotor: H.W. Lenstra

Sheltering is an immediate human need and determines well-being andhealth.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

Water is all around us and is vital for all aspects of life. Studying the various compounds and life forms that inhabit natural waters lets us better understand the world around us.

If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…

Een neuraal netwerk imiteert de werking van onze hersenen. Evolutionaire algoritmes gebruiken het principe van natuurlijke selectie om een complex probleem op te lossen. Deze vormen van natural computing worden ingezet om de diagnose van de ziekte van Parkinson accurater te maken, maar ook om bijvoorbeeld…

LIACS is a partner in RISE_SMA, an interdisciplinary, international network combining excellent scholars and practitioners to enable vigorous knowledge sharing and to develop solutions for contemporary challenges for Social Media Analytics (SMA).

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Promotor: R. Gill, Co-promotor: P. Massart

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

Promotor: Prof.dr. G.P. van Wezel

Cardiovascular syndromes are the major cause of death in Western societies.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Promotor: M.K. Richardson, Co-Promotor: F. Witte

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotores: A.H. Meijer, H.P. Spaink

De Faculty of Governance and Global Affairs

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

In this thesis we study bistable reaction-diffusion equations on lattice domains.

Promotor: W. T. F. den Hollander, F. H. J. Redig

Promotor: P.D. Grünwald