Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

Promotor: Prof.dr.ir. E. Deprettere

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

De Academy of Creative and Performing Arts is een samenwerkingsverband tussen de Leidse universiteit en de Hogeschool der Kunsten Den Haag'. (Deeltijd)studenten van de Leidse universiteit kunnen hier theoretisch en praktisch kunstvakonderwijs volgen, waarvan de studiepunten meetellen voor hun bachelor-…

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

Alumni-activiteit, New York

Het College van Bestuur heeft besloten dr. Bibi van den Berg met ingang van 1 september 2017 te benoemen tot hoogleraar Cybersecurity Governance binnen het Institute of Security and Global Affairs.

Het comité belast met vraagstukken over internationale handel van het Britse Lagerhuis (House of Commons) citeerde onlangs dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht aan het Leiden University College The Hague, in een rapport over de 'Continuing application of EU…

Op 8 maart zal Daniel Peat spreken bij de eerste jaarlijks conferentie van de recent opgerichte NAVO Mission Appeals Tribunal (MAT) die wordt gehouden in Napels.

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

De programmagroep Opvoeding en Ontwikkeling is verantwoordelijk voor onderwijs op zowel bachelor- als masterniveau, met speciale aandacht voor opvoeding en ontwikkeling.

Een overzicht van blogs, video's, podcasts, boeken, artikelen en activiteiten waarmee u zich verder kunt verdiepen in het koloniale en slavernijverleden.

Hoe kan formatieve assessment worden ingezet om het leren van docenten te bevorderen? Dit boek bevat diverse onderzoeken naar professionaliseringsaanpakken en cursussen waarin formatieve assessment wordt aangewend met het oog op het leren van docenten.

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Het Taalklavertje vier is een didactische handreiking voor leerkrachten Engels op school, pabo-opleiders Engels en pabo-studenten, met videovoorbeelden op dvd.

De rechtswetenschap is een verzamelnaam voor de 'juridica' en 'metajuridica'.

This proposed research uses ego-documents from visual artists that were not intended for publication to reassess the scholarly debate on the demise of the Russian Avant-garde aesthetic in the twenties and early thirties of the 20th century.

Religious Studies at Leiden University allows you to study a broad spectrum of religions and their manifestations.

Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Technologie in onderwijs.

Tijdens de specialisatie Leerproblemen leer je over algemene leerproblemen, zoals dyslexie, hyperlexie en dyscalculie, en leerproblemen veroorzaakt door ADHD, ADD of spraak- en taalstoornissen te herkennen en te behandelen. De specialisatie is gericht op de kennis en vaardigheden die nodig zijn voor…

Het Institute of Security and Global Affairs (ISGA) heeft een subsidie ontvangen van het EU Erasmus+ subsidieprogramma om een European Network on European Teaching Excellence (E-note) op te richten.

Het Centre for Public Values & Ethics (CPVE) is een interdisciplinair academisch expertisecentrum met als doel het verrichten en verspreiden van wetenschappelijk onderzoek naar waardengeladen vraagstukken in de publieke sector. In het bijzonder wordt gekeken naar de ethiek van de publieke ambtsvervulling…

Congres/symposium

Het Leiden Leadership Centre is een interdisciplinaire netwerkorganisatie. Als onderdeel van het Instituut Bestuurskunde van de Universiteit Leiden neemt het LLC een verbindende rol op zich door samen te werken met studenten, professionals uit de praktijk en wetenschappers vanuit verschillende disci…

Inspiratie van buiten en best practices van binnen de universiteit. Dat waren de belangrijkste ingrediënten van het symposium over inclusiviteit dat het Diversity Office van de Leidse universiteit op 22 november organiseerde.

Bibi van den Berg, Hoogleraar Cybersecurity Governance, verscheen afgelopen week verschillende keren in het nieuws over de internationale ransomeware-aanval en de impact daarvan.