Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.

Promotores: Bas Edixhoven, Guy Henniart

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

Promotor: G.P. van Wezel

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Promotor: S.M. Verduyn Lunel

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Promotores: J. Zaanen, A. Parnachev

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

Promotor: T.H. Oosterkamp

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Promotor: Prof.dr. T.H.W. Bäck

Promotores: J.C. van Houwelingen, S.A. van de Geer

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

This dissertation consists of two parts, with the common theme

Promotor: Prof.dr. H.W. Lenstra

Promotor: Prof.dr. M. Danhof

Promotor: Prof.dr. S.F. Portegies Zwart

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotor: Prof.dr. K.J. Batenburg

Promotor: Prof.dr. G.P. van Wezel

Promotor: P.D. Grünwald

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Promotor: Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Univ. de Bordeaux)

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Cardiovascular syndromes are the major cause of death in Western societies.

Promotor: Prof.dr. A.W. van der Vaart

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Promotor: K.J. Batenburg

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra

Promotor: B. van de Water