3,843 zoekresultaten voor “mobility en veiligheid in european more” in de Publieke website
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Breaking the witches' spell: towards steering the soil microbiome for volatile-mediated control of the root parasitic weed Striga
Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.
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Discovery of antibiotics and their targets in multidrug-resistant bacteria
Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Impact assessment modelling of matter-less stressors in the context of Life Cycle Assessment
Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs
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Biophysical feedbacks between seagrasses and hydrodynamics in relation to grazing, water quality and spatial heterogeneity
Consequences for sediment stability and seston trapping
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
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Dynamics and radiation from tidal disruption events
When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).
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Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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The ecological relevance of chemical diversity in plants
Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder
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Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
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Improving robustness of tomographic reconstruction methods
Promotor: Prof.dr. K.J. Batenburg
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Complex multiplication of abelian surfaces
Promotor: Peter Stevenhagen
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Not so smooth after all: resolving dust and gas structures in protoplanetary disks
A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Global distribution patterns of mycorrhizal associations
Mycorrhizas are symbiotic associations between soil fungi and most plant species.
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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The noise of the hunt: effects of noise on predator-prey relationships in a marine ecosystem
The effects of anthropogenic noise on interactions between predators and their prey are still little understood.
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Seeing voices: the role of multimodal cues in vocal learning
Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.
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Are we there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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Machine learning for radio galaxy morphology analysis
We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Radio galaxies near the epoch of reionisation
This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.
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Photon detection at subwavelength scales
Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Cathodic corrosion
Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.
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Cosmic tomography with weak gravitational lensing
We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.
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Quantifying the toxicity of mixtures of metals and metal-based nanoparticles to higher plants
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Breaking of ensemble equivalence for complex networks
For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.
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Understanding the value of social media metrics for research evaluation
The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.