4,298 zoekresultaten voor “proefschrift” in de Publieke website
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A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis
This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.
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Impact of land use changes on the human-elephant conflict
Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Non-target effects of GM potato: an eco-metabolomics approach
Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma
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Rationally designed peptide based functional biomaterials
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: M.K. Richardson, Co-Promotor: F. Witte
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Insights from scanning tunneling microscopy experiments into correlated electron systems
This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.
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Molecular characterization of copper-dependent enzymes involved in Streptomyces morphology
Promotor: G.P. van Wezel, Co-promotor: D. Claessen
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Reactivity of cobalt(II)-dichalcogenide complexes: correlation between redox conversion and ligand-field strength
The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.
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Neonicotinoids in nature: The effects on aquatic invertebrates and their role in ecosystems
This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Seeing voices: the role of multimodal cues in vocal learning
Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.
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Photothermal studies of single molecules and gold nanoparticles: vapor nanobubbles and conjugated polymers
Promotor: M.A.G.J. Orrit
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Are we there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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A search for transient reductions in the speed of sound of the inflaton in cosmological data, and other topics
Promotor: Prof.dr. A. Achucarro
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Machine learning for radio galaxy morphology analysis
We explored how to morphologically classify well-resolved jetted radio-loud active galactic nuclei (RLAGN) in the LOw Frequency Array (LOFAR) Two-metre Sky Survey (LoTSS) using machine learning.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame
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Casting light on the ƞ Carinae puzzle
Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura
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The alignment of galaxies across all scales
Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.
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Ontmoetingen tussen Marokkaanse Nederlanders en de Marokkaanse overheid : een antropologisch perspectief
Dit boek gaat over de relatie tussen de Marokkaanse overheid en Marokkaanse Nederlanders. Het perspectief van Marokkaanse Nederlanders staat hierin centraal. Wat zijn hun percepties over, ervaringen met en reacties op de zogenaamde ‘lange arm’ van Marokko?
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Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Design, synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
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Surviving embryogenesis: The extraembryonic serosa protects the insect egg against desiccation and infection
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee
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Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Taxonomy, systematics, and biogeography of Ficus subsection Urostigma (Moraceae)
Promotor: Prof.dr. P.C. van Welzen
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Photocatalytic redox reactions at the surface of liposomes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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The impact of obesity on the pharmacokinetics of drugs in adolescents and adults
Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst
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High-contrast imaging polarimetry of exoplanets and circumstellar disks
Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
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Governance of Innovation Project Management: Necessary and Neglected
Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries
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Higgs dynamics in the early universe
In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Plasmonic enhancement of one-photon- and two-photon-excited single-molecule fluorescence by single gold nanorods
This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.
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On transport properties of Weyl semimetals
Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink