4,421 zoekresultaten voor “history of science and the offers” in de Publieke website
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The music of language: exploring grammar, prosody and rhythm perception in zebra finches and budgerigars
Promotor: C.J. ten Cate
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Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)
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The role of zebrafish larvae for studying anxiety-like behaviour
The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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De wereld in het klein
Een kleine geschiedenis van het leven op aarde, verteld aan de hand van eilanden. Wat kunnen wij leren van deze werelden in miniatuur?
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Transnational Pentecostalism in the Age of #MeToo: Sexual Violence and Harassment from Lagos to Los Angeles
This initiative is intended to support generative research collaborations between and among scholars located in different geographical regions who wish to pursue focused, joint projects in any area of the study of religion.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Gauge theory and nematic order : the rich landscape of orientational phase transition
Promotor: J. Zaanen
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
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Insights into the mechanism of electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Dawn of the red and dead: stellar kinematics of massive quiescent galaxies out to z = 2
Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Turtles all the way down: multiscale simulations connecting star and planet formation
The formation of stars and planets happens over multiple scales, which can interact. In particular, planet formation happens in the dense, complex environment of star forming regions.
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Genomics driven metabolomics novel strategies for the discovery and identification of secondary metabolites
Promotor: T. Hankemeier, Co-promotor: R.J. Vreeken
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Psychologielab pakt Open Science op
‘Als je Open Science in de praktijk wilt doorvoeren, moet je minstens bij elke faculteit iemand hebben die onderzoekers op een laagdrempelige manier kan helpen met praktische problemen.’ Dorien Huijser begeleidde twee jaar de transitie naar de nieuwe manier van werkenbij het Brain and Development Research…
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Masterstudenten Data Science presenteren oplossingen aan Rijk en Tweede Kamer
Op 1 november 2019 presenteerden internationale masterstudenten Data Science van de Universiteit Leiden de uitwerking van hun dataconcepten aan hoge functionarissen van de Tweede Kamer en het Rijks I-Ecosysteem. Met de presentatie rondden ze dit deel van de mastercursus Data Science succesvol af.
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Effects of the early social environment on song and preference learning in zebra finches
Songbirds as vocal learners learn their songs and song preference from social tutors. Tutor choice for both song and preference learning are important to characterize for understanding individual learning performance and cultural transmission of song.
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The impacts and challenges of water use of electric power production in China
This thesis examines the impacts and challenges of water use of electric power system. This thesis found that there are large differences in water use of electricity technologies, with hydropower and thermal power being two large water users.
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Lines in the sand: behaviour of self-organised vegetation patterns in dryland ecosystems
Vast, often populated, areas in dryland ecosystems face the dangers of desertification.
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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The details of past actions on a smartphone touchscreen are reflected by intrinsic sensorimotor dynamics
Unconstrained day-to-day activities are difficult to quantify and how the corresponding movements shape the brain remain unclear. Read more
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Online Course International Law in Action: The Arbitration of International Disputes
This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…
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Mapping for meaning: using concept maps to integrate clinical and basic sciences in medical education
Het onderwerp van dit proefschrift is integratie van klinische kennis en kennis van de basisvakken in het medisch onderwijs en de rol die concept maps kunnen spelen in het expliciet maken van deze zogenoemde verticale integratie.
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Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union
1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…
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Science faculteiten van Universitas Indonesie en Universiteit Leiden versterken samenwerking
De Science faculteiten van de Universitas Indonesia (UI) en de Universiteit Leiden sloten op dinsdag 12 april een overeenkomst die de samenwerking tussen beide faculteiten versterkt. De overeenkomst werd getekend als afsluiting van een tweedaags bezoek van een delegatie uit Indonesië. De delegatie,…
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Boek over Integratie van Immigranten: "The Civic Citizens of Europe" door Moritz Jesse
Moritz Jesse, Universitair Hoofddocent Europees Recht aan het Europa Instituut, heeft zijn boek “The Civic Citizens of Europe: The Legal Potential for Immigrant Integration in the EU, Belgium, Germany, and the United Kingdom
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Leiden City of Science 2022: Interdisciplinaire lezing over supergeleiding
Lezing
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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Gender and transnationalism: Moroccan migrants and their descendants in the Netherlands, 1965-2000
Deelproject van
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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What’s CLIL about bilingual education? A window on Content and Language Integrated Learning pedagogies
In Nederland bieden ongeveer 130 van de 700 middelbare scholen een tweetalige stroom aan. Toch is er nog maar weinig wetenschappelijk onderzoek naar CLIL (content and language integrated learning). Met haar proefschrift wil Evelyn van Kampen (promovendus bij het ICLON) bijdragen aan een beter begrip…
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A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Leo Lucassen lid Academia Europaea
Leo Lucassen (hoogleraar Sociale Geschiedenis, Leiden University Institute for History) is onlangs op voordracht van de afdeling Geschiedenis en Archeologie van de Academia Europaea lid geworden van deze Europese academie voor wetenschappen.
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Math & Science class
Werk mee aan de ontwikkeling van de Math & Science class, gericht op de ontwikkeling van een academische houding. Sinds 2014 biedt de TU Delft voor 5 VWO scholieren de Math & Science Class aan. In dit onderwijsprogramma van twintig dagdelen worden gemotiveerde leerlingen uitgedaagd om op een meer academische…
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Do fungi differ? Understanding the mechanisms of mycorrhizal fungal impacts on soil C sequestration
How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.