Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

‘Het was nog nooit zo makkelijk om een Studium Generale reeks op te zetten.’ Met deze woorden bedankte organisator Tilman Grünewald spreker Frank den Hollander, die op maandag 20 februari de Studium Generale-reeks over complexe netwerken aftrapte.

Promotor: M. Ubbink, Co-promotor: G. Siegal

Bart Barendregt ontwikkelt een multimodale, methodologische toolkit.

Bart Barendregt ontwikkelt een multimodale, methodologische toolkit.

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

Mensen met een licht verstandelijke beperking (LVB) bevinden zich dikwijls in een soort niemandsland. Door de diversiteit van hun problemen doen deze mensen een beroep op uiteenlopende hulpverleningsinstanties van waaruit ze weer worden doorverwezen. Hierdoor krijgen ze vaak niet de ondersteuning die…

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

, Maliebaan 30, 2311 CC, Leiden

Herta Mohr, Maliebaan 30, 2311CC, Leiden

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

Van mensen met autisme leeft soms het beeld dat ze volledig op kunnen gaan in een bezigheid, zoals modeltreintjes of het oplossen van rubikskubussen. GZ-psycholoog en onderzoeker Bianca Boyer schrikt van de stelling: 'Dat ligt veel genuanceerder.'

Perspectieven zouden het fundament van een toekomstbestendig curriculum in alle onderwijssectoren moeten zijn

Lezing, Tuesday Talks: Science Insights

Een infrastructuur voor onderzoeksdata in computationele sociale wetenschappen

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Promotor: T. Schmidt

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Promotor: Prof.dr. G.P. van Wezel

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

In de specialisatie Cybersecurity Governance, onderdeel van MSc Crisis and Security Management, maak je kennis met de breedte, diepte en complexiteit van cybersecurity-uitdagingen. Deze track biedt je geavanceerde kennis over de governance- en regelgevingsstrategieën die beschikbaar zijn om deze uitdagingen…

Security and safety challenges rank among the most pressing issues of modern times. Challenges such as cyber-crime, terrorism, and environmental disasters impact the lives of millions across the globe. The course will introduce you to this broad theme in an increasingly complex world.

Lesgeven is een complex beroep. Docenten nemen veel beslissingen, bijvoorbeeld over wat ze onderwijzen, hoe ze dit gaan onderwijzen en hoe ze hun lessen kunnen aanpassen aan de behoeften van leerlingen. Dit vraagt een voortdurende ontwikkeling van nieuwe kennis en vaardigheden om expertise in alle facetten…

Cursus

Zuid- en Zuidoost Azië is één van 's werelds meest dynamische en diverse regio's. Wil je je verdiepen in de complexiteit van de geschiedenis, talen en culturen van dit gebied? En wil je je daarbij ook focussen op de snel ontwikkelende economieën? Dan is deze studie voor jou!

Promotie

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Een uitgave in de serie Handboeken Veiligheid, waaraan ook Erwin Muller, hoogleraar veligheid en recht bij het Instituur voor Strafrecht & Criminologie , een bijdrage heeft geleverd.

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

Op 10 oktober 2019 verdedigde Laure d'Hondt haar proefschrift 'Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.

Op 18 november 2020 verdedigde Mojan Samadi haar proefschrift 'Normering en toezicht in de opsporing'. Het promotieonderzoek is begeleid door promotor prof.mr. J.H. Crijns.

If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).