630 zoekresultaten voor “computational biology” in de Publieke website
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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The tension between nature conservation and economic valuation of ecosystem services
Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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On the optimization of imaging pipelines
In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…
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Daniel Zumel Gete
Wiskunde en Natuurwetenschappen
d.zumel.gete@cml.leidenuniv.nl | +31 71 527 2727
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Anagnostis Theodoropoulos
Wiskunde en Natuurwetenschappen
a.theodoropoulos@biology.leidenuniv.nl | +31 71 527 4882
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Peter van Welzen
Wiskunde en Natuurwetenschappen
peter.vanwelzen@naturalis.nl | +31 71 527 2727
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Sam Boerlijst
Wiskunde en Natuurwetenschappen
s.p.boerlijst@cml.leidenuniv.nl | +31 71 527 2727
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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A Paragenealogy of Computational Rationality
Lezing, Research Seminar
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Hans de Iongh
Wiskunde en Natuurwetenschappen
h.h.de.iongh@umail.leidenuniv.nl | +31 71 527 7461
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Assistant Professor in Protein Design
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Postdoc: Reactive scattering with electronic friction
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Meet Biology Leiden
Studievoorlichting
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Meet Biology Leiden
Studievoorlichting
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SAILS/ LIBC - Hackathon Computational Psychometrics
Lezing
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Vervolgopleidingen
Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
- Biology MSc diploma uitreiking
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Postdoc - Translational Pharmacology in antibiotic regimen development
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
- MSc Biology diploma ceremonies
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Surendra Balraadjsing
Wiskunde en Natuurwetenschappen
s.balraadjsing@cml.leidenuniv.nl | +31 71 527 2727
- Afstudeerceremonie MSc Biology
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Afstudeerceremonie MSc Biology
Afstudeerceremonie
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Afstudeerceremonie MSc Biology
Afstudeerceremonie
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Graduation Ceremony MSc Biology
Festival
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Summer School Computational Social Cognition 2024
Cursus, Summer School
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…
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Contact
Neem contact op met de afdeling Environmental Biology
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Integrated life cycle assessment and life cycle costing of concrete recycling in the Netherlands
Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…
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Simon Portegies Zwart in de Volkskrant over nieuw Jupitermaantje
Valetudo, zo hebben de astronomen het nieuw ontdekte Jupitermaantje genoemd. Het is een weerbarstig exemplaar dat dwars tegen haar soortgenoten in beweegt. In de Volkskrant reageert Leidse astronoom Simon Portegies Zwart op de bijzondere ontdekking.
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
- Diploma-uitreiking master Biology
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Projecten
Projecten van de afdeling Environmental Biology
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Onderwijs
Een uitgebreid overzicht van het onderwijs van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Publicaties
Een uitgebreid overzicht van de publicaties van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Onderzoek
Een uitgebreid overzicht van het onderzoek van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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Carole Tiberius benoemd tot hoogleraar Computerlinguïstiek: ‘Als je weet hoe systemen werken, kun je de beperkingen ervan beter inschatten’
ChatGPT, vertaalmachines en bots: voor Carole Tiberius zijn ze gesneden koek. 1 januari is ze benoemd tot hoogleraar Computerlinguïstiek. ‘Het vakgebied bestaat uit twee componenten: informatica en taalkunde.’
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Luka Narisha
Wiskunde en Natuurwetenschappen
l.l.narisha@cml.leidenuniv.nl | +31 71 527 5615
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Lan Dupuis
Wiskunde en Natuurwetenschappen
l.dupuis@cml.leidenuniv.nl | +31 71 527 2727
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Emily Strange
Wiskunde en Natuurwetenschappen
e.f.strange@cml.leidenuniv.nl | +31 71 527 2727
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Software en Data
Een uitgebreid overzicht van software en data beschikbaar gesteld door de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website
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PhD candidate in Network Science
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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Algebraic filters for filtered backprojection
Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit
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Modelling the role of cytotoxic T lymphocytes in tumour regression
Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.
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Multi-dimensional feature and data mining
In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.