1,815 zoekresultaten voor “fundamental richt” in de Publieke website
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Samenwerking
De Universiteit Leiden streeft naar impact van haar onderzoek en onderwijs op de samenleving. Veel van onze onderzoekers werken daarom samen met academische en maatschappelijke partners, overheidsinstellingen, non-gouvernementele organisaties en het bedrijfsleven.
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On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Frontiers of Nanoscience (NanoFront)
Kunnen we van quantum-verrassingen quantum toepassingen maken? Kunnen we het leven onderzoeken en opbouwen vanuit de nano-schaal?
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Automata-theoretic protocol programming
Promotor: F. Arbab
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
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Using soil inoculations for ecological restorations
How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Sweeping vacuum gravitational waves under the rug
One of the most important correlation functions in physics, especially in cosmology, is the energy density, which describes how much energy is present at each point in spacetime due to matter fields. A key contribution to the energy density of the primordial universe comes from gravitational waves (GWs),…
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Exploring charge transport properties and functionality of molecule-nanoparticle ensembles
Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen
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Surface Temperature and the Dynamics of H2 on Cu(111)
Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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The future of AI is human
Van zelfrijdende auto’s tot innovatieve medicijnontwikkeling, kunstmatige intelligentie (AI) gaat ons leven op uiteenlopende manieren fundamenteel veranderen. Onze computerwetenschappers bestuderen de technologie op een diep en fundamenteel niveau. Maar we zoeken ook naar medische toepassingen en antwoorden…
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…
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Using cryo-EM methods to uncover structure and function of bacteriophages
Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.
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Inducing spin triplet superconductivity in a ferromagnet
Promotor: J. Aarts
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Nano-scale electronic structure of strongly correlated electron systems
In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.
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Surface-structure dependence of water-related adsorbates on platinum
Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink
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Mining Sensor Data from Complex Systems
Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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Motivic invariants of character stacks
This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.
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Data Carpentry with R for Social Sciences and Humanities
Workshop
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Platinum electrochemistry through a magnifying glass
In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotores: Prof.dr. G.A. van der Marel, M. van Heel
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‘Extreem menselijk falen’ van hulpinstanties bij mishandeld pleegmeisje Vlaardingen
Jeugdhulpinstanties zijn ernstig tekort geschoten bij hulp aan het mishandeld pleegmeisje uit Vlaardingen, blijkt uit nieuw onderzoeksrapport. Hoogleraar jeugdrecht Mariëlle Bruning schoof aan bij Nieuwsuur: ‘Het gaat om extreem menselijk falen.’
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Vincent Delhomme spreekt over de betaalbaarheid van voedsel in het Europees Parlement
Vincent Delhomme hield op 22 januari 2025 een toespraak in het Europees Parlement in Straatsburg, over de betaalbaarheid van voedsel. Het event richtte zich op het bereiken van een evenwichtig voedselsysteem dat duurzaam, gezond en betaalbaar is.
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Interview Gianclaudio Malgieri over AI, Privacy en DeepSeek in The Unbrief
In een interview met Maya Plentz voor The Unbrief onderzocht Dr. Gianclaudio Malgieri, universitair hoofddocent Recht & Technologie bij eLaw, het snijvlak van AI-aangedreven zoektechnologieën en privacyrechten.
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Interim vice-decaan Maarja Beerkens richt zich op geluk en vertrouwen: ‘Heel trots op docenten en studenten’
Een nieuw gezicht versterkt het faculteitsbestuur van FGGA als vice-decaan. Maarja Beerkens komt van Bestuurskunde, waar zij al sinds 2010 doceert. De enthousiaste Haagse kijkt uit naar haar nieuwe uitdaging bij de Universiteit Leiden. ‘De mooiste universiteit van Nederland’.
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Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
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Molecular electronics: Controlled manipulation, noise and graphene architecture
Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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Leiden-Benghazi onderzoek naar conflicten rond onroerend goed in Libië
Dr. Suliman Ibrahim van het Van Vollenhoven Instituut doet in opdracht van het Ministerie van Buitenlandse Zaken onderzoek naar problemen rond onroerend goed in Libië.
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Aspecten van Joods leven in Roermond en Midden-Limburg 1275-2018
Op 28 oktober 2021 verdedigde Hein van der Bruggen zijn proefschrift en behaalde daarmee de doctorstitel.
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Algorithms for finite rings
Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Evaluatie en implementatie van innovatieve diagnostiek en behandelingen
Als een nieuwe methode is ontwikkeld om een (neuro-)psychologische aandoening of hieraan gerelateerde gedragsfactoren te herkennen en te behandelen, kan deze nog niet direct in de klinische praktijk worden ingezet. Eerst moet de methode geëvalueerd worden, bij voorkeur in gerandomiseerde, gecontroleerde…
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Cross-border Claims to Cultural Objects
Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).
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Fundamenteel onderzoek: Onderliggende mechanisme van ziekte en welzijn
Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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When data compression and statistics disagree: two frequentist challenges for the minimum description length principle
Promotor: P.D. Grünwald
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.