Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Including modelling as part of software development appears to have various benefits.

In dit proefschrift staat validiteit in de beoordeling van docentcompetenties centraal.

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De meeste studenten Notarieel recht vinden snel na afronding van hun masterprogramma een passende functie. Vaak als gevolg van een stage of juridische bijbaan werken ze in kernfuncties van juridische organisaties, ministeries, kantoren en bedrijven. In Nederland maar in toenemende mate internationaa…

Artful Mathematics: The Heritage of M. C. Escher

Op 26 september promoveert Cosmas Rai Amenorvi. Het Leiden University Centre for Linguistics feliciteert Cosmas!

Dit proefschrift beschrijft de ontwikkeling van een beoordelingsprocedure voor docenten, toegespitst op beginnende eerstegraads docenten Engels.

AI4Europe is één van de projecten, gefinancierd onder het Horizon Europe programma, dat verantwoordelijk is voor het beheer, de ontwikkeling en het faciliteren van het AI-on-Demand Platform (AIoD).

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

In dit artikel onderzoeken Lara van Osch, Sandra Groeneveld en Ben Kuipers de manier waarop leidinggend gedrag van eerstelijnsfunctionarissen in teams wordt ingezet om publieke waarde te creëren.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

In dit artikel gaan Joris Larik en Richard Ponzio in op het belang van de Summit of the Future om multilaterale samenwerking een nieuw leven in te blazen en te versterken in een tijdperk van toenemende concurrentie tussen de grootmachten.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Cardiovascular disease is the leading cause of death worldwide.

This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

Promotor: Prof.dr. A.G.G.M. Tielens

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

The research group Politics, Culture and National Identities 1789-present investigates a wide range of national political cultures in Europe and the Americas in the 19th and 20th centuries. Instead of only analyzing high politics (the acts of governments and political parties), the research group focuses…

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Promotor: Prof.dr. S. Haring

We brengen wetenschap bij u thuis! Doe mee aan onze online Biologische Bewegingsstudie!

Promotor: M. Ubbink, Co-promotor: G. Siegal

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

What is the role of the rebound effect in achieving environmental savings from transport eco-innovation? Are traditional definitions of the rebound effect adequate in the context of transformative innovations and multidimensional environmental issues?