Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

MINESCAPES invites PhD students from various disciplines to apply for participation in their 2024 summer school, taking place from May 31 to June 10, 2024. The Summer School will bring together students and scholars from the humanities, social sciences, and natural sciences to study mining landscapes…

Hoe kunnen we op een interdisciplinaire wijze de classificatie van migranten en mensen met een beperking bestuderen en onderzoekers van deze velden samenbrengen om raakvlakken met elkaar te vinden?

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

De opleidingen International Studies en Urban Studies hebben een nieuw adres. Na vijf jaar in het Wijnhavengebouw zijn ze verhuisd naar de Schouwburgstraat. ‘Het is goed om als Faculteit Geesteswetenschappen een eigen plek in Den Haag te hebben.’

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

Join-in courses zijn MA-cursussen over middeleeuwse onderwerpen gegeven binnen vastgestelde MA-programma's van de zes deelnemende universiteiten van de Onderzoekschool. Op aanvraag zijn deze vakken toegankelijk voor studenten van andere (Nederlandse) universiteiten. De cursusbelasting en het aantal…

Kevin speelt hedendaags repertoire dat zich onderscheidt doordat de lichamelijk handelingen die nodig zijn om deze muziek uit te voeren in de notatie van elkaar losgekoppeld zijn. Dit heet ook wel physical polyphonic notations, een unieke en relatief recente trend in de muziek waarbij naast de noten…

Promotor: Prof.dr. J. Schaye, Co-promotor: Marcello Cacciato

Bij Leiden University College The Hague staan Global Challenges centraal. Global Challenges zijn de grote, maatschappelijke uitdagingen van de 21ste eeuw waar we gezamenlijk een oplossing voor moeten vinden, zoals klimaatverandering, armoede, ongelijkheid, vrede en recht. Onze opleiding is opgesplitst…

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

Promotor: G.J.B. van Ommen

In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

Promotor: J. Kuiper

Promotor: G.P. van Wezel

This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.

Promotores: G. Persoon, R. Schefold

In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).

Online scriptiebegeleiding

Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Met een masterdiploma op zak heb je meer kans op een baan op academisch niveau. Na afronding krijg je de titel Master of Arts (MA).

Overzicht van de belangrijkste papyrologische websites

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

Promotor: J.W.M. Frenken

Promotie

Tijdens je studie al voor een maatschappelijke opdrachtgever aan de slag: bij Urban Studies gebeurt dat. Voor het vak Urban Studies in Practice voeren derdejaarsstudenten projecten uit voor publieke opdrachtgevers, zoals de gemeente Den Haag.

Isabelle Duyvesteyn wordt de nieuwe opleidingsvoorzitter van International Studies. Per 1 september staat de hoogleraar aan het roer van de grootste opleiding van de Faculteit Geesteswetenschappen.

This course provides an insider perspective into the work of international criminal courts and tribunals. You will learn about the investigation and prosecution of international crimes in The Hague.

Bij Cambridge University Press (CUP) verscheen onlangs van Ingrid Leijten het boek Core Socio-Economic Rights and the European Court of Human Rights. Het boek maakt onderdeel uit van de serie Cambridge Studies in European Law and Policy en heeft als onderwerp de bescherming van sociaaleconomische rechten…

The Grotius Centre, in collaboration with Duke Law School, will be hosting the Duke-Leiden Institute in Global and Transnational Law from 16 June to 17 July 2019 in The Hague, the International City of Peace and Justice. Applications for the second edition are now open!

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

De specialisatie Politics, Culture and National Identities, 1789 to the Present (research) van de Universiteit Leiden brengt je in de voorhoede van de nieuwe benadering van de manier waarop in Europa politiek en identiteit worden opgevat.

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.