777 zoekresultaten voor “health diseases” in de Publieke website
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Meeloopdag - Health & Medical Psychology
Studievoorlichting
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Meeloopdag - Health & Medical Psychology
Studievoorlichting
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Jordy van der Beek
Wiskunde en Natuurwetenschappen
j.g.van.der.beek@cml.leidenuniv.nl | +31 71 527 2727
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Maria Yazdanbakhsh
Faculteit Geneeskunde
m.yazdanbakhsh@lumc.nl | +31 71 526 5067
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webinar Population Health Management
Studievoorlichting
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Een zomer in het buitenland, maar dan digitaal
Een summer school volgen in het buitenland is voor veel studenten een mooie manier om hun vakantie zowel nuttig als leuk te maken. Maar door de vele reisrestricties waren ook de summer schools dit jaar vaak deels online. Toch was het animo er niet minder door. Hoe is het om digitaal in een ander land…
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Proefcollege Population Health Management
Studievoorlichting
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Tackling chronic respiratory disease in low-resource settings
Promotie
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Nieuwe stoffen remmen ontsteking in het brein
Leidse chemisch biologen, onder leiding van dr. Mario van der Stelt, hebben stoffen ontdekt die ontstekingsprocessen in de hersenen kunnen verminderen. Daarmee is een eerste stap gezet in de ontwikkeling van potentiële geneesmiddelen voor de behandeling van hersenziekten zoals de ziekten van Alzheimer…
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Capillary Electrophoresis-Mass Spectrometry based Metabolomics Approaches for Volume-restricted Applications
Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…
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Global Impact in Health Symposium
Symposium | Leiden2022
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Medical Delta Café: E-health
Lezing
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Meeloopdag - Occupational Health Psychology (geannuleerd)
Studievoorlichting
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Onderwijs
De sectie Gezondheids-, Medische en Neuropsychologie verzorgt onderwijs in de bachelor- en masterfase.
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Role of intestinal microbiota in cardio-metabolic disease
Promotie
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Advanced echocardiographic imaging in valvular and systemic diseases
Promotie
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Early diagnosis and management of celiac disease in childhood
Promotie
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Oxidative Stress in Chronic Diseases: Causal Inference from Observational Studies
Promotie
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Oxidants and antioxidants as targets for cardiovascular disease prevention
Promotie
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Viral gene therapy approaches for CRB1 retinal disease
Promotie
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Genetics and Life Course Epidemiology of Cardiometabolic Disease
Promotie
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4D-Flow MRI of Aortic and Valvular Disease
Promotie
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Developmental cell lineage dynamics in Bicuspid Aortic Valve disease
Promotie
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PhD candidate - biodiversity & society: the Dutch home as a multispecies space
Sociale Wetenschappen
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Mattijs Numans
Faculteit Geneeskunde
m.e.numans@lumc.nl | +31 71 526 9111
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Helena Vrabec
Faculteit Rechtsgeleerdheid
h.u.vrabec@law.leidenuniv.nl | +31 71 527 8838
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Peter de Knijff
Faculteit Geneeskunde
p.de_knijff@lumc.nl | +31 71 526 9537
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Winifred Gebhardt
Faculteit der Sociale Wetenschappen
gebhardt@fsw.leidenuniv.nl | +31 71 527 4084
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Strategies to Investigate Lipoprotein Metabolism and Combat Cardiometabolic Disease
Promotie
- Uitreiking master Population Health Management
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Advanced MRI-markers of cerebral small vessel disease
Promotie
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Cardiac CT for diagnosis and prognosis of coronary artery disease
Promotie
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Algorithm for Structural Variant Detection
Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.
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IBL Spotlights
Tijdens de IBL Spotlights bespreken onderzoekers van de afdeling Science Communication & Society hun nieuwste bevindingen en realisaties. Na de lezingen ben je welkom bij de borrel op de eerste verdieping van het Sylviusgebouw.
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Over het programma
Het verbinden van inzichten en perspectieven over leiderschap, governance en management met zorgvraagstukken staat binnen dit onderzoeksprogramma centraal.