1,074 zoekresultaten voor “experimental onderzoek near leesontwikkeling” in de Publieke website
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Wetenschappelijk onderzoek en onderwijs
Het LUBEC is nauw verbonden met de Universiteit Leiden.
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Onderzoekend leren en differentiëren
Het bedenken van een goede onderzoeksvraag kost tijd, hoe doe je dat met al die niveauverschillen in je klas?
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Nanowire based Tandem Solar Cells
In this project innovative technology for photovoltaics cells is developed and analysis of ecological and health related risks are explicitly accounted for.
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Not so smooth after all: resolving dust and gas structures in protoplanetary disks
A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Designing Ships using Constrained Multi-Objective Efficient Global Optimization
A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.
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Chemical tools to monitor and control proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.
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The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Clues from stellar catastrophes
Promotores: S.F. Portegies Zwart, E. M. Rossi
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Hydrodynamics and the quantum butterfly effect in Black Holes and large N quantum field theories
Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?
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Cavity quantum electrodynamics with quantum dots in microcavities
Promotor: Prof.dr. D. Bouwmeester
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CO2-Calculator
Development of GHG calculator for bio-electricity and heat.
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The Demographics of Protoplanetary Disks: from Lupus to Orion
The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.
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Thermostable Nanodiscs for the development of novel biopharmaceuticals
Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
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Characterization of age-associated immunity in atherosclerosis
Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…
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Empirical Legal Studies Leiden
Empirical Legal Studies in Leiden focust op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzoeken op het snijpunt van recht en gedrag, waarbij diverse soorten methoden worden gebruikt.
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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Single-electrolyte isotachophoresis: on-chip analyte focusing and separation
Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Origami metamaterials : design, symmetries, and combinatorics
In the first part of this thesis we study the geometry of folding patterns.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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Towards a greater understanding of the presence, fate and ecological effects of microplastics in the freshwater environment
This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Neonicotinoids in nature: The effects on aquatic invertebrates and their role in ecosystems
This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Using commitment to improve environmental quality
Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Assemblage and functioning of bacterial communities in soil and rhizosphere
Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae
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Nano-scale electronic structure of strongly correlated electron systems
In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Effects of slug herbivory on seedling recruitment in Brassica napus and B. rapa
Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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Computational modeling of angiogenesis : from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Matter into context: population- and community-level impacts of nanomaterials in freshwater ecosystems
The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…
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Platinum electrochemistry through a magnifying glass
In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Interaction of oxygen and carbon monoxide with Pt(111) at intermediate pressure and temperature: revisiting the fruit fly of surface science
Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink
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Soil organic amendments for climate-smart agriculture
Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…
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Bakker, ‘Do liberal norms matter?’, Acta Politica 2016
Een experimentele analse van de impact van liberale normen op steun voor of afwijzing van oorlogsvoering onder een groep mensen die zijn gesocialiseerd in een democratie (Nederland) en een groep die altijd heeft geleefd in een autocratie (China) toont aan dat het liberale gehalte in de democratische…