1,375 zoekresultaten voor “complex vaardigheden” in de Publieke website
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A radio view of dust-obscured star formation
Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.
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Effects of the early social environment on song and preference learning in zebra finches
Songbirds as vocal learners learn their songs and song preference from social tutors. Tutor choice for both song and preference learning are important to characterize for understanding individual learning performance and cultural transmission of song.
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Anisotropy, multivalency and flexibility-induced effects in colloidal systems
We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.
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Maak kennis met de opleiding Criminologie
Het opsporen, bestrijden en voorkomen van criminaliteit wordt steeds complexer. En veiligheid staat hoger dan ooit op de (inter)nationale agenda. Welke misdaden worden er gepleegd en door wie, waar en wanneer? Hoe zijn deze misdaden te voorkomen? Hoe help je slachtoffers/daders het best? En wat is de…
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A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis
This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
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Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
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Invertebrates on the edge
What invertebrates live in the fields and edges? Do the populations change with landscape complexity?
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier
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Het miljard deeltjes probleem
Promotor: Prof.dr. S. Portegies Zwart
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Development of an in vitro vascular network using zebrafish embryonic cells
One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.
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Terugkeerders uit Jihadistische strijdgebieden
In dit vierde rapport worden ontwikkelingen besproken ten aanzien van het beleid met betrekking tot personen die terugkeren uit jihadistische strijdgebieden, zogeheten ‘terugkeerders’, voor de periode januari 2017 tot medio december 2018.
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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VERBODEN TOEGANG! – Het recht op onderwijs voor meisjes, met een focus op Pakistan
Welke uitdagingen bestaan er voor meisjes in het uitoefenen van hun recht op onderwijs en in het bijzonder het krijgen van toegang tot onderwijs?
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Ladies-only! Empowerment and Comfort in Gender-segregated Kickboxing in the Netherlands
The experiences of ethnic ‘Other’ females have – until recently – been widely overlooked in the study of sport. There continues to be a need to produce critical scholarship about ethnic 'Other' girls and women in sport and physical culture, in order to represent their complex, multifarious and dynamic…
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Casting light on the ƞ Carinae puzzle
Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Scrum in secondary chemistry education
In het schoolvak scheikunde is de concept-context benadering ingevoerd. Hans Vogelzang onderzocht of de Scrum-methodologie kan helpen bij het vormgeven van lessen met deze benadering.
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De strijd van gelijkheid en vrijheid
Moeten alle mensen gelijk worden behandeld? En alle opvattingen? Een bevestigend antwoord op deze vragen ligt voor de hand.
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Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
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Brandweer - Studies over organisatie, functioneren en omgeving
De tweede, geactualiseerde druk van dit boek belicht de organisatie en het functioneren van de brandweer en brandweerzorg. In drie delen beschrijven wetenschappers en practitioners de turbulente ontwikkelingen van de afgelopen tien jaar, zoals de verbreding naar rampenbestrijding. Erwin Muller, hoogleraar…
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Total Synthesis of Alginate and Zwitterionic Sp1 Oligosaccharides
The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.
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Spectral signatures of breaking of ensemble equivalence
This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…
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Maak kennis met de opleiding Criminologie
Het opsporen, bestrijden en voorkomen van criminaliteit wordt steeds complexer. En veiligheid staat hoger dan ooit op de (inter)nationale agenda. Welke misdaden worden er gepleegd en door wie, waar en wanneer? Hoe zijn deze misdaden te voorkomen? Hoe help je slachtoffers/daders het best? En wat is de…
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Multi Modal Representation Learning and Cross-Modal Semantic Matching
Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.
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Cyber Security (MSc)
Ben jij een professional die een master wil doen? En heb jij een relevante achtergrond, zoals een HBO master of WO opleiding en enige jaren werkervaring? Dan kun je ervoor kiezen om je kennis in Cyber Security te verbreden en te verdiepen.
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Uyt saecke des doots
Al eeuwenlang wordt in Nederland bij overlijden belasting geheven over de verkregen erfenissen. De heffing van deze erfbelasting staat niet alleen ter discussie vanwege de vermeende dubbele heffing en het beklemmende aanknopingspunt, maar ook vanwege de mogelijkheden om via slimme juridische constructies…
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Self-assembly of flexible and rigid structures: from colloidal molecules to lattices
Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…
- Microben en het voedsel van de toekomst
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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De intergenerationele overdracht van extreme gedachtensystemen
Met de recente opkomst en val van IS uiten academici en beleidsmakers over de hele wereld hun bezorgdheid over het lot van kinderen van voormalige buitenlandse strijders. Zullen zij in de voetsporen van hun ouders treden? In dit artikel belichten Layla van Wieringen, Daan Weggemans en Marieke Liem de…
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Forces and symmetries in cells and tissues
The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.
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Supramolecular peptide amphiphile nanoparticles as a novel allergy vaccine platform
Bet v1, the major allergen in birch pollen, is one of the main causes of allergies such as asthma and rhino-conjunctivitis. It is the main cause of birch pollen allergy in humans.
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Economie & Samenleving
Benieuwd wat de bachelor opleiding Economie & Samenleving bij Universiteit Leiden jou te bieden heeft? In vogelvlucht laten we het je zien.
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Nuclear Quantum Effects in Solid Water
Ice, the solid state of water, plays an important role on our planet as well as the entire universe.Despite the fact that an individual water molecule has a very simple structure, its chemical bonding in the solid phase can be surprisingly complex.
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Temminck's Order. Debates on Zoological Classification: 1800-1850
“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.
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Over het project
De nieuwbouw voor de Faculteit der Wiskunde en Natuurwetenschappen is een belangrijke mijlpaal voor de Universiteit Leiden en de faculteit in het bijzonder. In drie fasen wordt een nieuw gebouw gerealiseerd. De eerste fase van het nieuwe gebouw is in 2016 in gebruik genomen en beslaat 45.000m2. Het…
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Good governance and the rule of law
Op welke manier ontwikkelt de ‘rule of law’ zich in Westerse samenlevingen in het licht van de opkomst en verspreiding van diverse digitale technologieën en hoe kan de rule of law invloed hebben op het gebruik en de verspreiding van deze technologieën.
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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The flexible listener: exploring zebra finch sensitivity to spectral and temporal sound features
Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Bridging the gap between physics and chemistry in early stages of star formation
A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Glue recipes and prehistoric brainpower
How do archaeologists test ideas about the evolution of the modern brain? Veni-researcher Geeske Langejans and then Master student Paul Kozowyk (Leiden University) prepared different Prehistoric glue recipes and tested these for strength in modern test machines at the Delft University of Technology.
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Cybersecurity & Cybercrime (BSc)
Sinds 2022 worden er in verhouding al meer mensen in Nederland slachtoffer van cybercrime dan van ‘normale’ criminaliteit. De bachelor Cybersecurity & Cybercrime leidt jou op tot allround cyberexpert, zodat jij de strijd met cybercriminaliteit en cyberterrorisme kan aangaan.
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Economics and Governance (MSc)
De specialisatie Economics and Governance van de Master Public Administration leert je probleemoplossende benaderingen te formuleren voor concrete beleidskwesties die zich bevinden op het snijvlak van economie en openbaar bestuur, met specifieke aandacht voor welvaartsstaten en markten. Deze specialisatie…