1,100 zoekresultaten voor “vroege many” in de Publieke website
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Long term dynamics of stochastic evolution equations
Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Agenda dynamics in the European Union : the interaction between the European Council and the European Commission in the policy domain of organized
The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Reactivity and Selectivity in Glycosylation Reactions
The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Exiopol
A new environmental accounting framework using externality data and input-output tools for policy analysis.
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Patterns on Spatially Structured Domains
We consider the propagation of electrical signals through nerve fibres.
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Real-time tomographic reconstruction
With tomography it is possible to reconstruct the interior of an object without destroying.
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Error bounds for discrete tomography
Promotores: K.J. Batenburg, B. Koren
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Ecology and conservation of spotted hyena in human dominated landscapes in northern Ethiopia
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen)
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Fulltime programme
Het schema hieronder geeft het curriculum weer van het eenjarige fulltime programma van de master Health, Ageing and Society in collegejaar 2024-2025.
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Single-molecule fluorescence in sequence space
The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…
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Matter into context: population- and community-level impacts of nanomaterials in freshwater ecosystems
The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Phylogeny and species delimitation within the moss genus Dicranum Hedw.
Promotor: Prof.dr. E. Smets, M. Stech
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…
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Anthracycline biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Migration and Mobility in the Early Roman Empire
Migration and Mobility in the Early Roman Empire by Luuk de Ligt and Laurens E. Tacoma (Eds.)
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Old Age in Early Medieval England, A Cultural History
Hoe dachten de anglosaksen over de ervaring van het ouder worden? Was het echt een gouden tijd voor de ouderen zoals werd gesuggereerd?
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Archeologen in podcast over eerste mensen in de Lage Landen
In aflevering 53 van de Leidse Studium Generale podcast Radio Horzelnest verkennen we de vroegste bewoningsgeschiedenis van ons land met archeologen Gerrit Dusseldorp en Yannick Raczynski-Henk. Samen schreven zij: ‘De eerste mensen in de Lage Landen’.
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Versoepelde criteria voor Amerikaanse terrorismelijst gelden ook in Nederland
Sinds 2013 voegen landen gemakkelijker namen toe aan de Amerikaanse terrorismelijst (TSDB), vertelt Jelle van Buuren in De Telegraaf.
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Esther van den Bos
Faculteit der Sociale Wetenschappen
bosejvanden@fsw.leidenuniv.nl | +31 71 527 6868
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Prehistorische jagers uit de Noordzee gebruiken mensenbot als wapens
De laatste jaren zijn er veel spectaculaire archeologische vondsten aangespoeld op de Nederlandse stranden. Zo ook bijna duizend spitsen van been en gewei uit het Mesolithicum (11,000-8000 v. Chr.). Tot nu toe was het niet bekend welke dieren de mesolithische jager-verzamelaars gebruikten om spitsen…
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De James Webb Space Telescope en het vroege heelal
Lezing, Kaiser Lente Lezing
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Materiaal: de moeder van innovatie
Niet het vernuft van de mens, maar materialen zijn de bron voor innovatie en vooruitgang. Dat concludeert archeoloog Maikel Kuijpers op basis van zijn onderzoek naar vakmanschap en materiaalbewerking in de Vroege Bronstijd.
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Studieprogramma
Bestudeer alle aspecten van het menselijk leven in het verleden en plaats je kennis in een breder, historisch perspectief.
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Utopia: Universal Three-dimensiOnal Passport for process Individualization in Agriculture
Vroege opsporing van gezondheidsrisico's Landbouwvoedingsmiddelen variëren van nature in hun gedetailleerde interne structuur. Om de vroege opsporing van gezondheidsrisico's als gevolg van besmetting of ziekten te vergemakkelijken, de rijpheid te voorspellen en de verspilling te minimaliseren, is het…
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Neurocognitief trainingsprogramma draagt bij aan de sociale cognitieve ontwikkeling van jonge kinderen met een extra X- of Y-chromosoom
De sociale ontwikkeling is één van de belangrijkste domeinen van kwetsbaarheid bij Jonge kinderen met een extra X- of Y-chromosoom. Het is daardoor voor hen uitdagender om sociale signalen te signaleren in hun omgeving, die te verwerken en er gepast op te reageren.
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VODAN Africa - FAIR Covid-19 data in Afrika en Azië
VODAN Africa is begonnen als een platform om toegang te bieden tot kritieke data die Afrika nodig heeft om de nieuwe COVID-19 te bestrijden. Het initiatief werd geïnspireerd door de ervaring met de uitbraak van het ebolavirus in Liberia in 2014: vroege opsporing vereist tracering van contacten. Het…
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Het Romeinse slavenvermogen in sociale context
Hoe functioneerde het slavenvermogen in de sociaal-juridische context van het Romeinse keizerrijk?
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2016
LIBC PUBLIEKSDAG 'ONZEKERE TIJDEN; EEN STRUIKEBLOK OF SPRINGPLANK?' (in Dutch)
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De onzichtbare last van cognitieve problemen bij multipele sclerose
Van de patiënten met multipele sclerose (MS) krijgt 34-65% vroeg of laat te maken met cognitieve problemen.
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De geboortepapieren van Nederland
Coos Huijzen & Geerten Waling, De geboortepapieren van Nederland. de unie van Utrecht, de apologie van Willem van Oranje en het plakkaat van verlating in hedendaags Nederlands (Amsterdam, 2014)
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Leiden Institute for Brain and Cognition
Het Leiden Institute for Brain and Cognition (LIBC) is een Leids Universitair netwerk dat zich richt op het stimuleren van interdisciplinaire samenwerking op het gebied van hersenen en cognitie. Daarnaast maakt het LIBC zich sterk voor wetenschappelijke valorisatie en outreach.
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Heterogenized molecular (pre)catalysts for water oxidation and oxygen reduction
Before the large scale use of renewable energy sources can be implemented in our society, the storage of electrical energy needs to be tackled. Storage the energy as hydrogen via the reduction of protons is a good option.
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Impact of plant hormones on growth and development of actinobacteria
Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.
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Understanding the Heterogeneity of Corporate Entrepreneurship Programs
In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…
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The Infrared Spectrum of Massive Protostars
We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?