Van 7-9 juni 2023 organiseert Global Transformations and Governance Challenges (GTGC) haar tweede internationale conferentie in Den Haag. Deadline voor inzendingen: 15 februari 2023.

LIACS is partner in het project 'Stereotypering in de Informatica'. Het project is een samenwerking tussen meerdere universiteiten en de Nederlandse landelijke expertorganisatie voor meisjes/vrouwen en wetenschap/technologie (VHTO), waarin onderzoek wordt gedaan naar de stereotypen die kinderen hebben…

Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Technologie in onderwijs.

Promotie

This thesis develops statistical methods for the analysis of high dimensional data: high dimensional networks reconstruction (Chapters 1-4), incorporation of prior information in networks reconstruction (Chapters 2-4), incorporation of prior knowledge in genetic association studies (Chapter 3).

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…

'Ik ben ervan overtuigd dat als er momenteel nog geen publieke omroep zou bestaan en we zouden bedenken dat het goed zou zijn om publiek geld (oftewel belastinggeld) te steken in journalistiek, het in niemand zou opkomen om dat geld te spenderen aan algemeen nieuws op radio, televisie en internet. Dat…

Van 8-10 juni 2022 organiseert Global Transformations and Governance Challenges (GTGC) haar eerste internationale conferentie in Den Haag. Deadline voor inzendingen: 22 april 2022.

EU human-centered digital

Op 9 september 2009 viert de opleiding Life Science and Technology (LS&T) haar tienjarig bestaan.

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Possible improvements for the assessment of abiotic depletion in LCA.

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Promotie

De opmars van het gebruik van laptops en tablets in het klaslokaal is in volle gang. Maar wat zijn de gevolgen van leren met een scherm? NEMO Kennislink sprak met Adriaan van der Weel, bijzonder hoogleraar in de moderne geschiedenis van het boek.

In februari stopt ze met onderwijzen en gaat ze met pensioen. Maar klaar met het vakgebied is ze nog niet: ze gaat haar PhD afmaken en er liggen nog vijf films op de plank die ze wil afronden.

The Leiden University Centre for Digital Humanities has awarded some small research grants to foster the developments of new digital research. These projects began in February 2018. On the 9th of October, these awardees will present their work, along with our PhD students.

Promotor: A.W. van der Vaart

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.