In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

The complexity of an intelligence problem determines to a great extent the certainty that can be provided by intelligence and security services.

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

The Eberhard-Karls Universität Tübingen organises a Winter school on the theme of Gender, Emotion and Monstrosity in the Middle Ages. Deadline for proposals: 1 August.

Diverse types of exoplanets such as gas giants on close-in orbits (hot Jupiters) and young massive giants on wide orbits (super Jupiters), with no analogs in the Solar System, pose challenges but also opportunities to our understanding of planet formation and evolution.

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

PUMA aims at composing a geological map of the urban mine of Amsterdam for a selection of metals. Where are main deposits of copper, iron and aluminium located, when will they become available for secondary production, in what state and shape are they?

The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.

An algorithm is discussed to compute the exponential representation of principal units in a finite extension field F of the p-adic rationals.

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

In dit artikel gaan Joris Larik en Richard Ponzio in op het belang van de Summit of the Future om multilaterale samenwerking een nieuw leven in te blazen en te versterken in een tijdperk van toenemende concurrentie tussen de grootmachten.

Brandon Valeriano (Cato Institute) and Aleydis Nissen (Leiden University) publish an article on the soft power of K-pop in The Diplomat.

The Research Training Group “Byzantium and the Euro-Mediterranean Cultures of War” invites scholars to submit paper proposals for a series of sessions on “Perceptions of Just War in the Middle Ages” at the IMC 2025. These sessions aim to explore the diverse theological, philosophical, legal, and cultural…

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L.B.F.M. Waters (UvA), Prof.dr. C. Dominik (UvA)

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Political scientist Matthew Longo (Leiden University) takes a detailed look at the evolution of border security in the United States after 9/11. Far from the walls and fences that dominate the news, he reveals borders to be thick, multi-faceted and binational institutions that have evolved greatly in…

In this dissertation several settings in the Online Learning framework are studied. The first chapter serves as an introduction to the relevant settings in Online Learning and in the subsequent chapters new results and insights are given for both full-information and bandit information settings.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

My work focuses on a class of astronomical objects called protoplanetary disks.

How were the Russians, under early modern conditions, able to incorporate this distant, undeveloped and, because frequent nomadic attacks, dangerous territory? And what role did the Kolyvan-Voskresensk plants play in this process?

Op 10 november 2016 organiseerde het Hazelhoff Centre for Financial Law een symposium over 'Ethics and Moral Hazard in the Banking Union' in het historische Academiegebouw van de Universiteit Leiden.

In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.

"To see, to hear, to touch, to kiss, and so on: Dealing with charters in the early Middle Ages." Guest lecture by Prof. Dr. Philippe Depreux (University of Hamburg): Tuesday 9 May 2023, 15.00-16.30

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…

De coronacrisis vraagt om een grensoverschrijdende aanpak en samenwerking tussen landen. De Europese Unie, echter, speelde tot dusverre geen sleutelrol. Politicoloog Amy Verdun (Universiteit Leiden) legt uit waarom.

Dit artikel onderzoekt hoe ISIS en de Taliban steun hebben gekregen door hun parallelle rechtssystemen.

Op 20 juni promoveert Camil Staps. Het Leiden University Centre for Linguistics feliciteert Camil!

This conference explores how reading experiences were shaped both by producers and users of vernacular books. By adopting an international and interdisciplinary perspective (combining book history, literary history, art history, religious studies, and history of knowledge) it aims to contribute to the…

In het kader van de zomerschool "Medieval Religon" geeft prof. Christopher M. Bellitto (Kean University) op 26 juni een keynote lezing getiteld "Politics and Religion in the Middle Ages and Today: Thoughts of an American Medievalist". Deze lezing is ook toegankelijk voor geïnteresseerden die niet deelnemen…

Op 26 september 2023 gaf Carlotta Rigotti een ​​lezing over de impact van de regelgeving op AI-toepassingen voor werving en selectie, tijdens de AI Lund Fika-to-Fika Workshop on Regulating High Risk AI in the EU.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Onder welke omstandigheden beperken paramilitaire groepen hun gebruik van politiek geweld? Dit artikel onderzoekt het gebruik hiervan door de PIRA.

In dit artikel bespreekt Vanessa Newby, universitair docent bij het Instituut Security and Global Affairs, geloofwaardigheid in vredesoperaties. Het artikel betoogt dat geloofwaardigheid in vredesoperaties moet worden opgebouwd met het oog op zowel afschrikking als samenwerking.

Samen met Erwin Muller, hoogleraar Veiligheid en Recht, ging Jasmina Mačkić op 8 september in gesprek met eerstejaarsstudenten over verschillende juridische en ethische dilemma’s en thema’s die de film ‘Eye in the Sky’ oproept.

De leden van de Zuid-Koreaanse K-popband BTS gaan het leger in en hoewel in Zuid-Korea een militaire dienstplicht geldt, betekent deze stap veel vanwege de opgelopen spanning op het Koreaanse schiereiland en in de rest van de wereld, schrijft postdoc Aleydis Nissen in een artikel in The Diplomat.

The Keuzegids Universiteiten 2015 (Guide for Study Choice Universities) has awarded Leiden University with five ‘Top Rated Programmes’: Mathematics, Biomedical Sciences, Greek and Latin Language and Culture, Liberal Arts & Sciences: Global Challenges and Philosophy.

Onder de gezamenlijke titel ‘Scarcity and the State’ verschenen onlangs twee Engelstalige boeken over de verdeling van schaarse publieke rechten (Intersentia 2016). Paul Adriaanse (UL), Frank van Ommeren (VU), Willemien den Ouden (UL) en Johan Wolswinkel (Tilburg University) voerden de redactie. Aan…

Promotores: H.W. Lenstra, B. Erez, Co-promotor: L. Taelman

Van de tanden van apen tot de microstructuur van botten: archeologe Simone Lemmers (31) is gefascineerd door botresten die ons meer vertellen over het verleden. Haar nieuwsgierigheid heeft geleid tot een zeer internationale carrière. Via het Verenigd Koninkrijk, waar ze getuige was van het Brexit-referendum,…

As part of the lecture series 'Religion Matters', Sven Gins (RUG) will speak about moving statues and other ingenuous devices in late medieval France. The lecture will take place on Wednesday, March 13, 17:00-18:00.

Promotie