Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…

In dit overzicht treft u een selectie aan van thema's waar de Leiden Islam Academie in is gespecialiseerd. De thema's zijn onderverdeeld in modules en kunnen per module, in de vorm van een cursus, gastcollege of workshop aangeboden of aangevraagd worden. De Leiden Islam Academie organiseert tevens regelmatig…

Afrika heeft een bevolking van 1,5 miljard mensen. In 2050 zal dit aantal naar verwachting stijgen tot 2,5 miljard. De impact van het continent op de wereldeconomie en samenlevingen, maar ook op het milieu, zal daardoor enorm toenemen.

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

Kunst en vrije tijd, Kunst en vrije tijd

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

Kunst en vrije tijd, Kunst en vrije tijd

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Promotor: Prof.dr. J.N. Kok

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

CMLCA is a software tool that supports the technical steps of the Life Cycle Assessment. The focus of the program is on advanced computational aspects of life cycle inventory calculations.

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

In this thesis we classify the pairs (p,G), where p is a prime number and G is a finite p-group possessing an intense automorphism, i.e. an automorphism that sends each subgroup of G to a G-conjugate, that is non-trivial and whose order is coprime to p.

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

In dit artikel doen Bart Schuurman en Sarah Louise Carthy onderzoek naar de oorzaken van terrorisme door verschillen en overeenkomsten tussen links-, rechts- en jihadistische extremisten te vergelijken.

Welke factoren (mens-dimensie en carnivoor-gerelateerd) zijn bepalend voor de menselijke tolerantie ten opzichte van grote carnivoren en voor de overlevingskansen van grote carnivoren in bossen met meervoudig gebruik?

World history is often framed in terms of flows of people and migration: humans coming ‘out of Africa’, the spread of farmers in the Holocene, Phoenician and Greek diasporas over the ancient Mediterranean, the colonization of the world by Europeans from the 16th century onwards. Together with his Exeter…

Parijse jongeren uit Tsjaad komen via Facebook in contact met jongeren in Tsjaad zelf. Veel beter kun je de mogelijkheden van sociale media niet weergeven voor mensen die door oorlog over de wereld verspreid zijn. Mirjam de Bruijn heeft een Vici-beurs voor onderzoek naar de impact van sociale media…

Op 9 juni presenteerde het Afrika-Studiecentrum het laatste boek van zijn gerenommeerde onderzoeker Stephen Ellis (1953-2015). This Present Darkness: A history of Nigerian organised crime kwam postuum uit. Oud-collega’s en vrienden herdachten Ellis, die beschouwd wordt als een van de belangrijkste Afrika-onderzoekers…

Voor het eerst in de geschiedenis zijn er twee winnaars van de Van den Bergprijs: de ‘traditionele’ voor de beste eindscriptie in het Nederlandstalige bachelorprogramma Politicologie en, per 2020, een student van de specialisatie International Relations and Organisations (IRO). Wouter de Rijks werk…

Afrika opstuwen in de vaart der volkeren door de sleutelcondities voor groei en vooruitgang in Azië te detecteren. Dat is het uiteindelijke doel van een Brits-Nederlands wetenschappelijk netwerk-in-oprichting. Leids onderzoek is leidend.

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

The LUGO Press is a student publication forum, rooted in academia and journalistic practices and published by the Leiden University Green Office.

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

The Titus Brandsma Institute and Radboud University Nijmegen organize an international conference on Thursday 19 and Friday 20 August 2021: Thomas a Kempis, his Works and their Reception.

Het Expertisebureau Diversiteit en Inclusie staat in nauw contact met verschillende studenten- en medewerkersnetwerken op het gebied van diversiteit en inclusie.

Er zijn wereldwijd vele open (leer)materialen beschikbaar, maar deze worden nog niet of zeer beperkt gebruikt in het onderwijs.