2,419 zoekresultaten voor “high throughput screening and microscopy” in de Publieke website
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Medical Delta café: translation models for drug discovery and development, 8 oktober 2013
Onze gemiddelde leeftijd gaat omhoog en de behoefte naar goede gezondheidszorg wordt steeds groter. Nieuwe medicijnen moeten op de markt komen maar kosten voor de ontwikkeling daarvan moeten omlaag. Tijdens het Medical Delta café op 8 oktober presenteren o.a. dr. Leo Price, dr. Jan de Sonneville en…
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Postdoc in Structures and Homotopy in Optimisation
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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The evolution and plasticity of life histories upon variation in nutrition: on aging focused integrative approach
Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)
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Citizenship, Migration and Global Transformations
Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…
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The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Colorectal cancer screening for average- and high-risk individuals Beyond one-size-fits-all
Promotie
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On the Power Efficiency, Low latency, and Quality of Service in Network-on-Chip
In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.
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evolution of chemical diversity in plants : pyrrolizidine alkaloids and cytochrome P450s in Jacobaea
Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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PhD candidate combinatorial drug discovery with macrocycles
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Young suns and infant planets: Probing the origins of solar systems
Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).
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Measuring gold molecular gas across cosmic time
Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…
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mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Kristian Rietveld
Wiskunde en Natuurwetenschappen
k.f.d.rietveld@liacs.leidenuniv.nl | +31 71 527 7038
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Pesticides and health – challenges and opportunities for exposure assessment
The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
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Assemblage and functioning of bacterial communities in soil and rhizosphere
Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae
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Compiling and Refining Environmental and Economic Accounts (CREAA)
CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.
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Transfusion Medicine and Cellular and Tissue Therapies (MSc)
This joint Master with the Autonomous University of Barcelona will the equip you with the necessary competences to play a key role in the emerging field of transfusion medicine. The programme includes both transfusion of blood components and hematopoietic transplants, cellular and tissue therapy, and…
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Betere screening kan huisarts helpen angststoornissen eerder te herkennen
Slechts een op de vijf minderjarigen met geestelijke gezondheidsproblemen zoals een angststoornis krijgt passende professionele hulp. Huisartsen herkennen vaak niet goed de signalen bij kinderen en jongeren, stelt psycholoog Semiha Aydin. Hoe kan het beter? Promotie op 23 februari.
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intermediates for polyurethane plastics for rigid foams/building insulation and coatings
What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?
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Joanne Mouthaan
Faculteit der Sociale Wetenschappen
j.mouthaan@fsw.leidenuniv.nl | +31 71 527 6781
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Nieuwe transmissiemicroscoop voor elektronen met lage energie
Natuurkundige Daniël Geelen ontwikkelde tijdens zijn promotie een nieuwe microscoop die laag-energetische elektronen gebruikt. Zulke elektronen zijn minder schadelijk voor biologische en organische materialen. Geelen promoveert op 31 mei.
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Glucocerebrosidase and glycolipids: In and beyond the lysosome
The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Tax and Society: Building a Sustainable and Fair Tax System
Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.
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International Peace and Justice Master Fund – Law and Society Scholarship
Master
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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Topological phases and phase transitions in magnets and ice
The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.
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Bio-Pharmaceutical Sciences and Science Communication and Society (MSc)
Deze opleiding bereidt je voor op een rol als verbindende schakel tussen wetenschap en de samenleving. Je verwerft de kennis en vaardigheden waarmee je andere wetenschappers en leken kunt informeren over belangrijke wetenschappelijke ontwikkelingen in jouw vakgebied.
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Representation and Political Parties
‘Representation and Political Parties’ is een van de zeven onderzoeksclusters binnen het programma ‘Institutions, Decisions and Collective Behaviour’. De aangesloten onderzoekers richten zich op de rol die burgers spelen binnen een democratie en op de vertegenwoordiging van kiezers door politici.
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Legitimacy and Justice
‘Legitimacy and Justice’ is een onderzoekscluster binnen het programma ‘Institutions, Decisions and Collective Behaviour’. De wetenschappers die hierin actief zijn houden zich bezig met de legitimiteit en rechtvaardigheid van politieke instituties. Zij kijken in het bijzonder naar de relaties tussen…
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Postdoctoral researcher in: Radicalisation measurement and prevention (1.0 FTE)
Governance and Global Affairs, Institute of Security and Global Affairs
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Sustainable Chemistry and Biotechnology
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Innovative diagnostics and treatments
Hoe meer we leren over een (neuro-)psychologische of lichamelijke aandoening en de hieraan gerelateerde gedragsfactoren, hoe beter we deze niet alleen kunnen signaleren, maar ook behandelen. Het is dus belangrijk dat recente inzichten over (neuro-)psychologische problemen en daaraan gerelateerde gedragsfactoren…
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Asian Modernities and Traditions
The research profile ‘Asian Modernities and Traditions’ (AMT) aims to raise the strength and visibility of research, teaching and dissemination of Asian studies at Leiden University.
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LIBC Onderzoeksfaciliteiten
Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):
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Transfusion Medicine and Cellular and Tissue Therapies (MSc)
Dit masterprogramma voorziet je van de nodige competenties om een sleutelrol te spelen in het opkomende gebied van transfusiegeneeskunde. Het huidige concept omvat zowel transfusie van bloedbestanddelen als hematopoëtische transplantaties, cel- en weefseltherapie en immunotherapie. Gebieden die geïntegreerd…
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webinar Transfusion Medicine and Cellular and Tissue Therapies
Studievoorlichting
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Governance and Global Affairs
Binnen de faculteit Governance and Global Affairs zijn 3 instituten gevestigd:
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2 Assistant Professors in Generative AI and Human-centered AI
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Transitional justice and liberal post-conflict governance : synergies and symmetries, frictions and contradictions
Wat betekent het om “gerechtigheid te brengen” in een overgangsperiode? Gerechtigheid voor wat, gerechtigheid voor wie, en met welk doel?
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Terrorism, Counterterrorism and Radicalization
De database is ontwikkeld door het Centre for Terrorism and Counterterrorism van de Campus Den Haag.
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Culture and Politics (MA)
De masterspecialisatie Culture and Politics van de Universiteit Leiden bevordert kritische perspectieven op complexe culturele kwesties als onlosmakelijk onderdeel van de wereldpolitiek.
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Arts and Culture (MA)
De master Arts and Culture van de Universiteit Leiden biedt je een topniveau kwalificatie op maatwerk op het gebied van kunst en cultuur.
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Princes and Prophets: Democracy and the Defamation of Power
Op 1 juni 2022 verdedigde Tom Herrenberg het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. P.B. Cliteur en prof.dr. B.R. Rijpkema.