Electron microscopy has become an extremely important techniquein a wide variety of elds.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

This thesis describes a study from both a theoreticaL and an experimental point of view.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Het doel van deze faciliteit is om het biomedisch onderzoek te versnellen door toegang te bieden tot geavanceerde licht- en elektronenmicroscopie en door het delen van expertise over monstervoorbereiding, beeldvormingsmodaliteiten, gegevensopslag en beeldanalyse.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

The dissertation describes TEM experiments on heterogeneous catalysts.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Promotor: J. Zaanen, Co-Promotor: V. Juricic

Promotores: G.W. Canters, T.J. Aartsma

Promotie

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

De Tweede Kamer, het kloppend hart van de Nederlandse democratie, bestaat tweehonderd jaar. Zestien gezaghebbende auteurs, waaronder Henk te Velde, Joris Oddens en Diederik Smit, schetsen in dit mooi uitgevoerde jubileumboek op toegankelijke wijze de ontwikkeling van deze volksvertegenwoordiging vanaf…

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Prof.dr. E.J.J. Groenen, Co-Promotor: M. Huber

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Onderzoeksgroepen in het Quantum Matter & Optics onderzoeksprogramma onderzoeken elektronische eigenschappen van interacties van materie en lichtmaterie, met de nadruk op quantuminformatie.

Promotor: Prof.dr. J.W.M. Frenken

Natuurkundige Daniël Geelen ontwikkelde tijdens zijn promotie een nieuwe microscoop die laag-energetische elektronen gebruikt. Zulke elektronen zijn minder schadelijk voor biologische en organische materialen. Geelen promoveert op 31 mei.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

Promotores: T.H. Oosterkamp, N. de Jonge

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Triplet superconductivity refers to a condensate of equal-spin Cooper pairs (pairs of electrons with equal spin).

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.