1,079 zoekresultaten voor “digital and audiovisual methods” in de Publieke website
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Principal algebraic actions of the discrete Heisenberg group
Promotor: Prof.dr. W.T.F. den Hollander
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Real-time tomographic reconstruction
With tomography it is possible to reconstruct the interior of an object without destroying.
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Phylogeny and species delimitation within the moss genus Dicranum Hedw.
Promotor: Prof.dr. E. Smets, M. Stech
- Thesis Lab: "The Source Course" (3 ECTS)
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Efficient and Automatic Tomographic Reconstruction Algorithms
In this thesis we present several methods to automate tomographic reconstruction algorithms and several novel tomographic reconstruction algorithms with the focus on being easily applicable and efficient to use.
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Basic Program 2024-2025
The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).
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Stereotypering in de informatica
LIACS is partner in het project 'Stereotypering in de Informatica'. Het project is een samenwerking tussen meerdere universiteiten en de Nederlandse landelijke expertorganisatie voor meisjes/vrouwen en wetenschap/technologie (VHTO), waarin onderzoek wordt gedaan naar de stereotypen die kinderen hebben…
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Studieprogramma
De studie leert je om mee te denken over de beleidsmatige aanpak van belangrijke kwesties binnen onze samenleving. Het gaat vaak om complexe vraagstukken, waar je zelf de weg in moet vinden. Het studieprogramma maakt je daar stapsgewijs klaar voor.
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Correction methods for measurement error in epidemiologic research
Promotie
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Prior information and variational Bayes in high dimensional statistical network inference
This thesis develops statistical methods for the analysis of high dimensional data: high dimensional networks reconstruction (Chapters 1-4), incorporation of prior information in networks reconstruction (Chapters 2-4), incorporation of prior knowledge in genetic association studies (Chapter 3).
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Charge transport properties of Ru-complex molecules: the influence of humidity
I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.
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Online Course International Law in Action: The Arbitration of International Disputes
This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…
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Starter grant 1
EU human-centered digital
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Tien jaar Life Science and Technology
Op 9 september 2009 viert de opleiding Life Science and Technology (LS&T) haar tienjarig bestaan.
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ALL-IN meta-analysis
Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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How to scale clearance from adults to children for drugs undergoing hepatic metabolism?
The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.
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Complex Patterns in Streams
The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…
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Combining monitoring with run-time assertion checking
Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Learning from small samples
Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
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Interstellar Catalysts and the PAH universe
Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Adriaan van der Weel in Kennislink over de gevolgen van digitaal lezen
De opmars van het gebruik van laptops en tablets in het klaslokaal is in volle gang. Maar wat zijn de gevolgen van leren met een scherm? NEMO Kennislink sprak met Adriaan van der Weel, bijzonder hoogleraar in de moderne geschiedenis van het boek.
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LUCDH Symposium
The Leiden University Centre for Digital Humanities has awarded some small research grants to foster the developments of new digital research. These projects began in February 2018. On the 9th of October, these awardees will present their work, along with our PhD students.
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Mattijs Numans
Faculteit Geneeskunde
m.e.numans@lumc.nl | +31 71 526 9111
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Antonius Johannes Rabelink
Faculteit Geneeskunde
a.j.rabelink@lumc.nl | +31 71 526 2148
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Inge Ligtvoet
Faculteit der Geesteswetenschappen
i.j.g.c.ligtvoet@hum.leidenuniv.nl | +31 71 527 1956
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Liwen Meng
Faculteit der Sociale Wetenschappen
l.meng@fsw.leidenuniv.nl | +31 71 527 2727
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Peter van der Zwan
Faculteit Rechtsgeleerdheid
p.w.van.der.zwan@law.leidenuniv.nl | +31 71 527 8560
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Peter de Knijff
Faculteit Geneeskunde
p.de_knijff@lumc.nl | +31 71 526 9537
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
garnefski@fsw.leidenuniv.nl | +31 71 527 3774
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Tommy van Avermaete
Universitaire Bibliotheken Leiden
t.o.van.avermaete@library.leidenuniv.nl | +31 71 527 2818
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Alies Jansen
Faculteit der Geesteswetenschappen
e.jansen@hum.leidenuniv.nl | +31 71 527 1255
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Abdourahamane Idrissa Abdoulaye
Afrika-Studiecentrum
a.idrissa.abdoulaye@asc.leidenuniv.nl | +31 71 527 3372
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Susan van den Brink
Wiskunde en Natuurwetenschappen
s.van.den.brink@cml.leidenuniv.nl | +31 71 527 2727
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Daphne Wong-A-Foe
Faculteit der Sociale Wetenschappen
d.l.wong-a-foe@fsw.leidenuniv.nl | +31 71 527 2727
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Federico De Musso
Faculteit der Sociale Wetenschappen
f.de.musso@fsw.leidenuniv.nl | +31 71 527 2727
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Carola Hein
Faculteit der Sociale Wetenschappen
c.m.hein@fsw.leidenuniv.nl | +31 71 527 2727