1,726 zoekresultaten voor “mathematical and statistical modelling” in de Publieke website
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Statistics & Data Science (MSc)
De masteropleiding Statistics & Data Science is een tweejarige master waarbij een diep doorgronde introductie wordt gelegd aan de algemene filosofie en methodologie van statistische modellen, statistisch modelleren, data analyse en data science, met de voornaamste focus op toepassingen in levens- en…
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Data Science and Artificial Intelligence (BSc)
Bij Data Science & Artificial Intelligence leer je hoe je functies van het brein, zoals denken, geheugen, leren en aandacht in modellen kunt gieten. Deze kennis kun je gebruiken om computers en systemen op vergelijkbare of betere manieren te laten functioneren.
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Md Faysal Tareq
Wiskunde en Natuurwetenschappen
m.f.tareq@cml.leidenuniv.nl | +31 71 527 2727
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Anjali Pandit
Wiskunde en Natuurwetenschappen
a.pandit@chem.leidenuniv.nl | +31 71 527 4198
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Peter van Bodegom
Wiskunde en Natuurwetenschappen
p.m.van.bodegom@cml.leidenuniv.nl | +31 71 527 7486
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Matthijs van Leeuwen
Wiskunde en Natuurwetenschappen
m.van.leeuwen@liacs.leidenuniv.nl | +31 71 527 7048
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Baoxiao Liu
Wiskunde en Natuurwetenschappen
b.liu@cml.leidenuniv.nl | +31 71 527 5615
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Huub de Groot
Wiskunde en Natuurwetenschappen
groot_h@chem.leidenuniv.nl | +31 71 527 4539
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Nuno De Mesquita César de Sá
Wiskunde en Natuurwetenschappen
n.q.de.mesquita.cesar.de.sa@cml.leidenuniv.nl | +31 71 527 2727
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PhD Historisch onderzoek naar levensloop en 'ouderen' in medische literatuur en beleid
Geesteswetenschappen, Instituut voor Geschiedenis
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Postdoc: Reactive scattering with electronic friction
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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Niet langer naar de wereld kijken als ‘the West and the rest’
Kunsthistoricus en hoogleraar Kitty Zijlmans heeft een missie: ze wil af van het idee dat het westen de kunstwereld domineert. Niet langer ‘the West and the rest’, maar de uitwisseling tussen ideeën en culturen centraal stellen in de kunstgeschiedenis. ‘Dan zie je dat er zoveel uitwisseling geweest…
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Medicijnafbraak bij kinderen: wat gebeurt er in de nieren?
Welke dosis geneesmiddel geef je een kind? Dat hang voor een groot deel van af van hoe snel hun nieren dit medicijn weer uit het bloed verwijderen. Om ethische redenen is het onmogelijk om dit bij jonge patiënten te meten. Promovenda Sinziana Cristea combineerde verschillende modelleermethodes en veel…
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Dr. Peter Grünwald benoemd tot hoogleraar Statistisch leren
Dr. P.D. (Peter) Grünwald is per 1 november bij de Faculteit der Wiskunde en Natuurwetenschappen benoemd tot hoogleraar Statistisch leren.
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Staging cerebral amyloid angiopathy: From marker to model
Promotie
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Understanding the Heterogeneity of Corporate Entrepreneurship Programs
In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Evolutionary Developmental Biology of Bitterling Fish
We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…
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Going global to local: achieving agri-food sustainability from a spatially explicit input-output analysis perspective
The global agri-food system plays a critical role in food security and environmental issues.
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Revealing the nature of new low-frequency radio source populations
It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood
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Evolutionary diversification and historical biogeography of Orchidaceae in Central America with emphasis on Costa Rica and Panama
In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Solving multiplication and division problems
Latent variable modeling of students' solution strategies and performance
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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How to scale clearance from adults to children for drugs undergoing hepatic metabolism?
The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.
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Enlightening the Primordial Dark Ages
This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.
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representation: An experimental study on teacher-student gender congruence and students’ perceived abilities in math
Onderzoek naar representatieve bureaucratie heeft vaak de positieve prestatie-effecten bevestigd van bureaucratieën die de demografische kenmerken van hun cliënten weerspiegelen. Er is echter weinig bekend over de onderliggende mechanismen op individueel niveau die tot deze resultaten leiden.
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Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal
Op 16 december 2019 verdedigde Jan-Harm de Villiers zijn proefschrift 'The Anthropomorphic Hegemony of Subjectivity: Critical Reflections on Law and the Question of the Animal'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Cliteur.
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Corporate venture management in SMEs: evidence from the German IT consulting industry
Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)
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Stap 4. Vergelijken en beslissen
Hoe maak je nu de definitieve keuze voor een masteropleiding?
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Does it still hurt?
The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.
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Morphodynamic equilibria in tidal inlet systems: sensitivity to geometrical variations
A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.
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Systems diagnosis of chronic diseases, explored by metabolomics and ultra-weak photon emission
Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
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Drie Leidse wetenschappers ontvangen NWO ENW-KLEIN subsidie voor vernieuwend onderzoek
De herkomst van Surinaamse rijst, een digitale tweeling van de aarde en een groot big-data project aan de Chileense hemel: drie Leidse wetenschappers ontvangen een ENW-KLEIN subsidie voor vernieuwend, fundamenteel onderzoek.
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Prof.dr. Willem Heiser koninklijk onderscheiden
Hoogleraar psychologie Willem Heiser (statistische methoden en datatheorie) is op 31 januari 2014 benoemd tot Ridder in de Orde van de Nederlandse Leeuw. Na zijn afscheidsrede ontving hij de koninklijke onderscheiding wegens uitzonderlijke wetenschappelijke, maatschappelijke en bestuurlijk-organisatorische…
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Deze onderzoekers lossen met wiskunde medische problemen op
Twee Leidse wetenschappers laten zien hoe ze met wiskunde onze gezondheidszorg kunnen verbeteren. Daniel Gomon ontwikkelde een model om de kwaliteit van de zorg in ziekenhuizen te monitoren. Marta Spreafico werkt aan een app die artsen helpt bij de behandeling van een type kanker. ‘Het is geweldig wanneer…
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EuDEco Report on the legal analysis (D2.2)
D2.2 comprises the in-depth legal analysis of the initial heuristic model, focused on addressing, in more detail, the main legal concerns for data reusers in the European data economy. This detailed analysis of the legal propositions presented in D2.1 is supplemented by an analysis of the technological,…
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Innovative (electro-driven) sample preparation tools for metabolomics study of muscle aging
This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.
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Assessing the link between television consumption and the attitudes toward people living with HIV/AIDS in Chile
We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…
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Single-molecule microscopy in zebrafish embryos
Single-Molecule Microscopy (SMM) techniques constitute a group of powerful imaging tools that enable researchers to study the dynamic behavior of individual molecules.
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Lezingen bij Science
Van zwarte gaten tot kunstmatige intelligentie en van medicijnonderzoek tot data science: welkom in de fascinerende wereld van de Faculteit der Wiskunde en Natuurwetenschappen. Geregeld geven onze onderzoekers, studenten en gasten publieke lezingen over hun werk. U bent van harte uitgenodigd.