643 zoekresultaten voor “fmri use” in de Publieke website
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Statistical physics and information theory for systems with local constraints
Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Cleared for take-off, Game-based learning to prepare airline pilots for critical situations
Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.
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CO2-Calculator
Development of GHG calculator for bio-electricity and heat.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Positive representations of algebras of continuous functions
If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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spFRET studies of nucleosome dynamics modulated by histone modifications, histone variants and neighboring nucleosomes
Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
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Isotopes and the characterization of extrasolar planets
Diverse types of exoplanets such as gas giants on close-in orbits (hot Jupiters) and young massive giants on wide orbits (super Jupiters), with no analogs in the Solar System, pose challenges but also opportunities to our understanding of planet formation and evolution.
- About this minor
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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LIBC Onderzoeksfaciliteiten
Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):
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Research project The Power of Evidence
De wetenschappelijke onderbouwing van beleid wordt cruciaal geacht voor goed bestuur. Maar ondanks de overvloed aan beschikbare kennis uit onderzoek en evaluaties, weten we nog maar weinig over de daadwerkelijke invloed die dergelijke evidence heeft op overheidsbeleid. Het onderzoeksprogramma ‘Power…
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Sustainability Series
We are very excited to announce our Sustainability Series for 2023-2024. Each month an interactive workshop will be organised that discusses a specific theme of sustainability. Interested about sustainability? Do not hesitate to sign up to our events !
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Biotic ligand models
Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)
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Partners
Ons onderzoeksprogramma werkt samen met allerlei partners om ons doel, het zo snel mogelijk naar de kliniek brengen van wetenschappelijke ontdekkingen, te bereiken.
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Structured Parallel Programming for Monte Carlo Tree Search
The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.
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Publicaties door Erfgoed Gezocht
Lees hier de publicaties die over het Erfgoed Gezocht project zijn verschenen.
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Geometry and arithmetic of del Pezzo surfaces of degree 1
This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.
- Perzisch 5
- Perzisch 6 Plus
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Constraints on large-scale implementation of BioSolarCells, Early stage assessment of environmental value propositions
What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?
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Onderzoeksgroep Governance of Crises
De onderzoeksgroep ‘Governance of Crises’ bestudeert verschijnselen, dynamiek en spelers als het gaat om crisisbeheersing. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoekgroep.
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Musems, Collections and Society | Yearbook 2020
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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SiTaSol
What are the life-cycle environmental impacts and risks to human health and ecosystems of a III-V/Si PV system? How can these be expected to change when the system is deployed at industrial scale? What are the most favourable recycling scenarios?
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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Waves and Patterns in Discrete Media: Bridging the Gaps
What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body
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Positioning of current Environmental tools & an outlook to the future
Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Free verse poetry writing (English spoken)
Kunst en vrije tijd, Kunst en vrije tijd
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New Foundations for Separation Logic
The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?
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Korean Painting: 'Drawing Various Chrysanthemums & Bamboo’
Kunst en vrije tijd, Kunst en vrije tijd
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Functionele architectuur van het brein blootgelegd
Een internationaal samenwerkingsverband van hersenonderzoekers van 35 onderzoekscentra – van de VS tot China – waaronder het Leiden Institute for Brain and Cognition (LIBC), heeft van meer dan 1400 gezonde vrijwillers resting-state functionele MRI-data verzameld en online beschikbaar gesteld voor on…
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Basic Program 2024-2025
The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).
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Effects of glufosinate-ammonium on off crop vegetation
Description of Effects of glufosinate-ammonium on off crop vegetation.
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PhD candidate on soil fungal ecology
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)