761 zoekresultaten voor “human rights” in de Publieke website
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Plant occurrence in space and time: the importance of land use, habitat structure, and pollination mode
Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Gene regulation in embryonic development
The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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Onderwijs
De programmagroep Leer- en Gedragsproblemen in het Onderwijs is verantwoordelijk voor onderwijs op het gebied van leerproblemen binnen de bachelor- en masteropleidingen van het Instituut Pedagogische Wetenschappen.
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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Fulltime programme
Het schema hieronder geeft het curriculum weer van het eenjarige fulltime programma van de master Health, Ageing and Society in collegejaar 2024-2025.
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The flexible listener: exploring zebra finch sensitivity to spectral and temporal sound features
Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Education and Child Studies (MSc)
In de masteropleiding Education and Child Studies kies je een specialisatie in één van de deeldisciplines van de pedagogische wetenschappen. In alle specialisaties staat de wetenschappelijke vorming van studenten voorop.
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Shekhar Kolipaka
Faculteit der Sociale Wetenschappen
s.s.kolipaka@fsw.leidenuniv.nl | +31 71 527 3451
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Roy Remme
Wiskunde en Natuurwetenschappen
r.p.remme@cml.leidenuniv.nl | +31 71 527 5610
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Alexander van Oudenhoven
Wiskunde en Natuurwetenschappen
a.p.e.van.oudenhoven@cml.leidenuniv.nl | +31 71 527 7473
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Capillary Electrophoresis-Mass Spectrometry based Metabolomics Approaches for Volume-restricted Applications
Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…
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Online Course International Humanitarian Law
In this course, you will gain a deep insight into the rules that govern armed conflict, and aim to mitigate human suffering on the battlefield. You will explore the why and how of International Humanitarian Law, followed by the different types of conflict.
- Human Perspectives: Diaspora and Migration in Global History (Leiden)
- Van werken naar helpen: geneesmiddelontwikkeling.
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Genomen van bacteriën in kaart brengen om infectieziektes te bestrijden
Hoe passen bacteriën zich aan aan een nieuwe leefomgeving? Hoe zitten genomen van bacteriën precies opgevouwen in cellen? Dat gaat een internationaal team van wetenschappers onderzoeken, onder leiding van de Leidse biochemicus Remus Dame. Het Human Frontier Science Program heeft hiervoor een subsidie…
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Building bridges: a multidisciplinary approach to controlled human hookworm infection
Promotie
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Aged human osteochondral explants as biomimetic osteoarthritis model
Promotie
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Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Self adjuvanting immunopeptides: Design and synthesis
Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.
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A macro level assessment of material circularity
A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
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Development and application of cryo-EM tools to study the ultrastructure of microbes in changing environments
Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Deepening the uncertainty dimension of environmental Life Cycle Assessment: addressing choice, future and interpretation uncertainties.
LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.
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Social Dimensions of Crane and Wetland Conservation in African Rural Landscapes: Insights from Kenya, Uganda and Zimbabwe
This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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Towards a Sustainable and Circular Metals Economy
In-use stocks of products can be considered as intermediaries between human needs and the physical world.
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Contact
Heb je nog vragen over de masterspecialisatie Digital Media in Human Development? Neem dan gerust contact met ons op!
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Contact
Heb je nog vragen over de masterspecialisatie Applied Neuroscience in Human Development? Neem dan gerust contact met ons op!
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Non-invasive assessment of human brown adipose tissue
Promotie
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Jolanda van der Vliet ‘Betere internationale bescherming milieuvluchtelingen’
Op donderdag 7 mei jl. promoveerde Jolanda van der Vliet op haar proefschrift ‘The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach’. De verdediging vond online plaats. Jolanda werkte aan dit proefschrift met begeleiding van het…
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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Kwetsbare groepen en Ongelijkheid
Binnen het Instituut voor Strafrecht en Criminologie wordt vanuit uiteenlopende disciplines onderzoek verricht naar Kwetsbare groepen en Ongelijkheid.
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Prof. Tim Koopmans
Tim Koopmans is een van de grote denkers in de geschiedenis van de Nederlandse en Europese rechtswetenschap. Hij doceerde rechten als professor in Leiden en andere universiteiten, waaronder Gent, Cambridge en Utrecht. Bovendien was hij rechter bij het Europese Hof van Justitie en Advocaat-Generaal bij…
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Bestuursbureau en expertisecentra
Het Bestuursbureau ondersteunt het College van Bestuur en draagt zorg voor de beleids- en besluitvorming.
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Development of nanoparticulate adjuvants based on aluminium salts
The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.
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Algorithm for Structural Variant Detection
Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.
- Hoe komt het dat geneesmiddelen werken?