1,886 zoekresultaten voor “ass” in de Publieke website
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Suzanne Assen
Wiskunde en Natuurwetenschappen
s.m.e.assen@lic.leidenuniv.nl | +31 71 527 4653
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Sietze van As
Faculteit Archeologie
s.van.as@arch.leidenuniv.nl | +31 71 527 2727
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Graphene as biological sensor
Wangyang Fu
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Francesco Ragazzi, Students as suspects?
Beleid dat erop is gericht radicalisering tegen te gaan, ondermijnt het vertrouwen en de sociale cohesie binnen onze samenleving.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Synthesis of cyclic peptides as bioconjugation platforms
Cyclic peptides are investigated as a platform to induce different orientations between various ligands.
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Career College: Working as a Consultant
Loopbaan en solliciteren
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Synthetic peptides as tools in chemical immunology
This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.
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Iminosugars as glucosylceramide processing enzymes inhibitors: design, synthesis and evaluation
This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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Ginsenosides as selective glucocorticoid drugs: agonists, antagonists, and prodrugs
Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Let Them Roar: Small States as Cyber Norm Entrepreneurs
Sinds de United Nations Group of Governmental Experts on the Developments in the Field of Information and Telecommunications in the Context of International Security (UN GGE) elf aanbevelingen heeft gedaan over verantwoordelijk staatsgedrag omtrent cyberspace is er een discussie gaande over internationale…
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The Rome Statute as Evidence of Customary International Law
Op 9 april 2019 verdedigde Yudan Tan haar proefschrift 'The Rome Statute as Evidence of Customary International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. W.A. Schabas.
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One million spins as study tools and study objects
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Galactic substructures as tracers of dark matter and stellar evolution
One of the most important puzzles in modern astrophysics is the nature of dark matter.
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Supramolecular peptide amphiphile nanoparticles as a novel allergy vaccine platform
Bet v1, the major allergen in birch pollen, is one of the main causes of allergies such as asthma and rhino-conjunctivitis. It is the main cause of birch pollen allergy in humans.
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Transnational Terrorism as a Threat: Cross-Border Threats
Dit artikel analyseert de transnationaliteit van terroristische organisaties, waaronder fondsenwerving, communicatie, alliantievorming en doelselectie.
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Sovereignty as a Vocation in Hobbes's Leviathan
Hoye stelt dat het fundamentele fundament van Hobbes' Leviathan grootmoedige staatkunde belichaamt, waarin soevereinen natuurlijke rechtvaardigheid nastreven, die zich manifesteert als eminente
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Supramolecular peptide amphiphile nanoparticles as a novel allergy vaccine
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Cyclophellitol and its derivatives: synthesis and application as beta-glycosidase inhibitors
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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Dynamic hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
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Child Marriage as a Choice: Rethinking agency in international human rights
Op 18 maart 2020 verdedigde Hoko Horii haar proefschrift 'Child Marriage as a Choice: Rethinking agency in international human rights'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. G.A. van Klinken (UvA).
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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The learning portfolio as a tool for stimulating reflection by student teachers
Het onderwerp van deze studie is het portfolio dat wordt gebruikt bij een lerarenopleiding als instrument om bij docenten in opleiding reflectie op hun ontwikkeling als docent te stimuleren.
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development of an assessment procedure for beginning teachers of English as a foreign language
Dit proefschrift beschrijft de ontwikkeling van een beoordelingsprocedure voor docenten, toegespitst op beginnende eerstegraads docenten Engels.
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Why It Is Wrong to Use Student Evaluations of Professors as a Measure of Teaching Effectiveness
In this article, Eamon Aloyo argues that university supervisors should not use student evaluations of teachers as a measure of teaching effectiveness.
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Otjes & Louwerse, ‘Parliamentary questions as strategic party tools‘ (West European Politics)
Waarom dienen kamerleden schriftelijke vragen in? Hoe kiezen zij hun onderwerpen en de te bevragen minister? De politicologen Simon Otjes (Universiteit Groningen) en Tom Louwerse (Universiteit Leiden) onderzochten de praktijk in de Tweede Kamer en constateerden dat kamervragen deel uitmaken van de ‘voortdurende…
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Repackaging in South–North Policy Learning: The Chilean Model of Pension Reform as a Lopsided Exportschlager
In dit artikel vatten Kristin Makszin en Achim Kemmerling bewijs samen over hoe het VK en de VS leren van het Chileense pensioenmodel, maar beide landen slagen er niet in krediet toe te kennen of de lessen te vervormen.
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Decoding supplier codes of conduct with content and text as data approaches
Door de groeiende populariteit van zelfregulering door bedrijven om problemen in de leveringsketen aan te pakken, staat maatschappelijk verantwoord ondernemen in het middelpunt van de belangstelling. In dit artikel analyseren Jaroslaw Kantorowicz, Sarah Vandenbroucke en Yvonne Erkens de gedragscodes…
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Lodge & Boin, COVID-19 as the ultimate leadership challenge: making critical decisions without enough data
De coronacrisis is de ultieme test voor bestuurders. Hoe houden nationale politieke leiders zich staande in hectische, dynamische tijden? Martin Lodge (London School of Economics and Political Science) en (Arjen Boin (Instituut Politieke Wetenschap Universiteit Leiden) bekijken de ervaringen opgedaan…
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Unveiling the third dimension: Vertical structure as a probe of planet forming conditions
Promotie
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Peer education as an opportunity for practicing respect for sexual and gender diversity
Het centrale doel van dit proefschrift is inzicht verschaffen in hoe de implementatie van een peer educator-interventie van invloed kan zijn op de houding van leerlingen tegenover LHBT-leeftijdgenoten en op de relatie tussen deze houdingen en reflectie over burgerschap.
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Women as Agents of Change: How has Women’s Political Mobilization Restructured Political Networks and Changed Local Governance?
Gaat de toenemende deelname van vrouwen aan verkiezingen in ruraal India het bestuur verbeteren?
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Vollaard, ‘The 2017 Dutch parliamentary elections: A fragmented picture as Rutte and Wilders draw their battle lines’
De Tweede Kamerverkiezingen die staan gepland voor maart 2017 zullen resulteren in een versnipperd parlement en een lastige kabinetsformatie, aldus de politicoloog Hans Vollaard (Universiteit Leiden) in een bijdrage aan het EUROPP-blog.