Psycholoog Bernadet Klaassens heeft een groot fMRI-onderzoek opgezet naar het effect van medicijnen op hersennetwerken bij veroudering en de ziekte van Alzheimer. Het leverde een unieke dataset op en zicht op een nieuwe methode om medicijnen te ontwikkelen voor patiënten met Alzheimer.

Van de nieuwe podcast van Hortus tot de 'conference call' bingo: in sneltreinvaart moesten alle studenten, docenten en andere medewerkers van de Universiteit Leiden deze week omschakelen naar thuis werken en studeren. Dat betekenden werkkamers uitruimen, online lesgeven vorm geven en talloze apps installeren…

Door de coronamaatregelen van het kabinet kwam de EL CID ineens op losse schroeven te staan. Toch kan de jaarlijkse introductieweek op 5 augustus van start gaan. Hoe heeft het EL CID-bestuur dat voor elkaar gekregen? Een kijkje achter de schermen door de ogen van voorzitter Mirte Haanappel.

This thesis mainly focuses on multimodal understanding and Visual Question Answering (VQA) via deep learning methods. For technical contributions, this thesis first focuses on improving multimodal fusion schemes via multi-stage vision-language interactions.

In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.

How and to what extent the historic house (re-)constructs identity through image-making in China.

Using the principles of Industrial Ecology in Environmental Policy making in two cases: transition to a hydrogen economy and chlorinated compounds.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Promotor: Prof.dr. H.A.G. Wijshoff

In the first part of this thesis we study the geometry of folding patterns.

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

This dissertation presents new cryptographic protocols, which can be divided into two families.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

As per January 1st, Niek Strohmaier is part of Kifid’s arbitration committee.

Promotores: S.J. Edixhoven, P.Parent

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Sheltering is an immediate human need and determines well-being andhealth.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

We consider the propagation of electrical signals through nerve fibres.

In this thesis integral points on affine del Pezzo surfaces are studied.

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

Promotor: A. Kros

What is the current relevance of the ethics of counterterrorism and what is the added value of ethics support within the practice of counterterrorism?

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

An account of the total of material flows going in, out and through Amsterdam.

This dissertation investigates the energy and material related impacts of the transition towards a low-carbon heating system in the Netherlands, in the context of its 2050 climate and circular economy policy goals.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee