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2 zoekresultaten voor “targeted therapy” in de Publieke website

• Uncovering vulnerabilities in triple-negative breast cancer Onderzoeksoutput

  Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

• Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors Onderzoeksoutput

  Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.