Promotor: R.D. Gill, F. Taroni

The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

In this article, Eamon Aloyo argues that university supervisors should not use student evaluations of teachers as a measure of teaching effectiveness.

Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

Tijdens het spelen van online games kunnen conflicten ontstaan. Novin, Bos, Stevenson en Rieffe onderzochten in dit artikel welke factoren maken dat de ene jongere daarbij bozer reageert dan de andere. In hun realistisch nagemaakte spel begon de zogenaamde medespeler plotseling te mopperen dat de deelnemer…

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Promotor: Prof.dr. T.H.W. Bäck

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Samenwerkend leren in het hoger onderwijs: ontwerp, implementatie en evaluatie van groepsleeropdrachten

In welke mate zijn beoordelingen op basis van een videodossier betrouwbaar, generaliseerbaar en valide?

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Johan van Wilsem, strateeg onderzoeker bij de Algemene Rekenkamer, gaf afgelopen academisch jaar het eenmalige keuzevak ‘Policy Evaluation in Practice’, (Beleidsevaluatie in de praktijk) aan studenten van de masteropleiding Crises and Security Management (CSM). Een schot in de roos, voor zowel studenten…

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It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

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A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

Om de kwaliteit van ons onderzoek te waarborgen, beoordeelt een commissie van externe experts onze instituten.

This thesis describes the evaluation of novel natural products with antibacterial activity enabled by total chemical synthesis.

Hoe kan wetenschap op een verantwoorde manier worden uitgevoerd, beoordeeld en aangestuurd? Het zijn vragen die ook de universiteit zelf van het grootste belang zijn. Het Centrum voor Wetenschaps- en Technologiestudies (CWTS) bestudeert wetenschappelijk onderzoek en zijn relatie met technologie, innovatie…

Promotor: Prof.dr. M. Danhof

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

De wetenschappelijke onderbouwing van beleid wordt cruciaal geacht voor goed bestuur. Maar ondanks de overvloed aan beschikbare kennis uit onderzoek en evaluaties, weten we nog maar weinig over de daadwerkelijke invloed die dergelijke evidence heeft op overheidsbeleid. Het onderzoeksprogramma ‘Power…

What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.

What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

What are the life-cycle environmental impacts and risks to human health and ecosystems of a III-V/Si PV system? How can these be expected to change when the system is deployed at industrial scale? What are the most favourable recycling scenarios?

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

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The project falls in the context of the EU Thematic Strategy on the Sustainable Use of Natural Resources (COM(2005)670). The Institute for Environment and Resources (IES) of the Joint Research Centre (JRC) has developed three sets of decoupling indicators. Such indicators require the definition of a…

Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…

Promotor: W.T. de Groot