In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.

Promotor: Prof.dr. P.C. van Welzen

Promotor: Prof.dr. B.R. Katzy, Prof.dr. J. de Vries

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

What impact does a mid-season wildfire have on grassland invertebrates?

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

Promotor: Roeland M.H. Merks

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

The applications of studying the early development of insects range from agriculture to material science.

Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

An interdisciplinary collection of the best international scholarship on Muslim youth.

Promotor: Prof.dr. B.R. Katzy

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

De European Cooperation in Science and Technology (COST) heeft een netwerksubsidie toegekend voor het project GoodBrother. Vanuit de Universiteit Leiden heeft Bart Custers, hoogleraar Law & Data Science en directeur van eLaw, Centrum voor Recht en Digitale Technologie, aan het voorstel meegeschreve…

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