1,040 zoekresultaten voor “roos were in roos environmental” in de Publieke website
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Chemistry in embedded disks: setting the stage for planet formation
To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.
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Platinum electrochemistry through a magnifying glass
In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Functional analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice
Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang
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Modulation of plant chemistry by rhizosphere bacteria
Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.
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New polymyxin antibiotics for old problems: addressing nephrotoxicity and resistance
Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…
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Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Promotores: A.P. IJzerman, H.W.T. van Vlijmen
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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SDG Report
The following report discusses a survey on the topic of the Sustainable Development Goals that was distributed among researchers at Leiden University in the month of November 2021.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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Novel detectors and algorithms for electron nano-crystallography
Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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Above- and belowground interactions in Jacobaea vulgaris: zooming in and zooming out from a plant-soil feedback perspective
In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Resolving gas-phase metallicity in galaxies
Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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Student for a Day at BSc Security Studies | Lecture 'Environmental Factors and the Conflict in Syria '
Studievoorlichting
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Archeologen en historici trekken samen op bij onderzoek uniek scheepswrak
In 1984 werd in de Waddenzee een bijzonder goed bewaard scheepswrak gevonden. Het fluitschip verging waarschijnlijk aan het einde van de 16e eeuw. Ondanks decennia van onderzoek is er nog niet eerder met een interdisciplinair perspectief naar het scheepswrak gekeken. De Rijksdienst voor Cultureel Erfgoed…
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Nieuwe universitaire podcast: Enkeltje Wetenschap
In de allereerste aflevering van Enkeltje Wetenschap vertelt bijzonder hoogleraar Ariadne Schmidt over het leven van vrouwen in de vroegmoderne tijd. Je hoort over Leidse viswijven, criminele dames en verzetsvrouw Magdalena Moons.
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Lisa Bruil wint de Kees Bakker-Prijs
Studente Lisa Bruil van het Instituut Biologie Leiden mocht op 16 januari de jaarlijkse prijs van de Stichting Prof. dr. K. Bakker-Fonds in ontvangst nemen voor haar uitmuntende resultaten als bachelorstudent.
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Toekomst in onderzoek naar publiek leiderschap
Op woensdag 11 april vond de feestelijke uitreiking van de leiderschapsagenda plaats die het Leiden Leadership Centre samen met de praktijk ontwikkelde. De onderzoeks- en ontwikkelagenda: ‘Verder met publiek leiderschap’ werd overhandigt aan burgemeester Pauline Krikke en rector magnificus Carel Stolker.…
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Hoe ranzig zijn scooterhelmen? Leidse biologiestudenten zochten het uit
Met een practicum kijken hoeveel soorten bacteriën en schimmels te vinden zijn in een helm van een leenscooter. Dat deden Leidse biologiestudenten op verzoek van het Algemeen Dagblad (AD). En wat blijkt: soms is een helm zo vies als een vaatdoekje.
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Moleculaire Biotechnologie naar het Sylvius
De onderzoeksgroep Moleculaire Biotechnologie (MBT) is in de week van 10 december verhuisd naar de vierde verdieping van het Sylvius Laboratorium. De verhuizing van de groep van Professor Gilles van Wezel zorgt ervoor dat alle Microbiologie en Microbiële Biotechnologie onderzoeksgroepen van de Universiteit…
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Media enthousiast over slimme sterrenkunde-student
Masterstudent Arend Moerman is erin geslaagd de hoogst mogelijke score te halen voor zijn afstudeeronderzoek naar zwarte gaten: een 10. Het komt gemiddeld maar één keer in de tien jaar voor dat een student sterrenkunde dat cijfer haalt. Zijn opmerkelijke prestatie werd opgepikt door nationale media…
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Environmental assessment and guidance for the future development of offshore wind energy
Promotie
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Sustainability: An Elaboration and Application of the System of Environmental-Economic Accounting for Indonesia
Promotie
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Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Promotie
- Young Academy Leiden Outreach Grant
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‘Voedsel is onbetwistbaar een grote factor in ons watergebruik’
Van waterzuiveringsinstallaties tot een lekkere warme douche, de CO2-uitstoot ten gevolge van het watergebruik in de VS staat gelijk aan dat van 50 miljoen auto’s die een jaar lang rondrijden. In The Washington Post raadpleegt journalist Tik Root verschillende experts om te leren over manieren om ons…
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Anthropogenic effects on links between macro-invertebrate diversity and ecosystem functioning
How are links between macro-invertebrate diversity and ecosystem functioning influenced by anthropogenic pressures?
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Solution for Critical Raw Materials - an European Export Network (SCRREEN)
Where and how are critical materials currently used and how can this information be used to develop scenarios about their future demand.
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CERA - Certification of Raw Materials
CERA (CErtification of RAw Materials) is a four-year project that will develop a standardized certification scheme ensuring environmental, social and economic sustainability in extraction, processing, trading and manufacturing of all mineral raw materials. It will guarantee traceability of certified…
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Swimming Bass under Pounding Bass: fish response to sound exposure
Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn
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PNEC-pro
PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).
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Expanding the coverage of ecosystem services in life cycle assessment: an interdisciplinary venture
To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
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Impact assessment modelling of matter-less stressors in the context of Life Cycle Assessment
Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs
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Bugs and birds and landscape complexity
What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?