Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)

Firearms and violence in Europe–A systematic review by Katharina Krüsselmann, Pauline Aarten, Marieke Liem

Op donderdag 23 mei ging Nederland naar de stembus om te kiezen wie ons land gaan vertegenwoordigen in het Europees Parlement. En wij waren niet de enigen: 375 miljoen Europeanen mogen hun stem uitbrengen en zullen zo de 751 Europarlementariërs kiezen. Maar wat doen Europarlementariërs eigenlijk? Mendeltje…

The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…

SEAtrans: an interdisciplinary research project that aims at studying the dynamics and processes of transitions in society-nature interactions in Southeast Asian societies.

The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…

How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?

How to bring together different footprints into an integrated family and what are the synergies? What are the roles of inventory analysis and characterization in measuring individual footprints and how these affect a footprint family? How to benchmark environmental footprints against related planetary…

Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Promotor: Prof.dr. H.J.A. Rottgering

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

LIACS is a partner in RISE_SMA, an interdisciplinary, international network combining excellent scholars and practitioners to enable vigorous knowledge sharing and to develop solutions for contemporary challenges for Social Media Analytics (SMA).

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst

How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?

PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).

The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

Promotor: Prof.dr. T. Hankemeier

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: W. Jiskoot, Co-promotor: A. Hawe

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

What invertebrates are available to feed nestlings in an agricultural landscape of varied complexity?

Promotor: G.R. de Snoo

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Cardiovascular disease is the leading cause of death worldwide.

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)

Promotor: S.M. Verduyn Lunel

Promotor: T.H. Oosterkamp

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

This dissertation consists of two parts, with the common theme

Promotor: Prof.dr. G.P. van Wezel

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.