1,234 zoekresultaten voor “random works in random environmental” in de Publieke website
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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Gauss's theorem on sums of 3 squares, sheaves, and Gauss composition
Promotor: Bas Edixhoven, Promotor: Qing Liu
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Towards a single-molecule FRET study of Frauenfelder's nonexponential rebinding of CO in myoglobin
Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.
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Establishing State Responsibility in the Absence of Effective Government
Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).
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Global Fields and Their L-functions
Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Shaping the pharmacokinetic landscape for renally cleared antibiotics in obesity
The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.
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Redox Interconversion between Metal Thiolate and Disulfide Compounds
In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.
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Adsorption and catalysis on Pt and Pd monolayer-modified Pt single crystal electrodes
The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.
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Causal Discovery from High-Dimensional Data in the Large-Sample Limit
Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets
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Growth and Transport properties of (Rare Earth)TiO3 / SrTiO3 interfaces
This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.
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Hierarchical Systems
The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.
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Topics in the arithmetic of del Pezzo and K3 surfaces
Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk
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Student projects
To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Software development by abstract behavioural specification
The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.
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Fundamenteel onderzoek: Onderliggende mechanisme van ziekte en welzijn
Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.
- Activiteiten
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CE-MS for metabolomics: advancing performance and detection sensitivity
The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.
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Lava worlds: characterising atmospheres of impossible nature
Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune.
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Systemic Accountability of the European Border and Coast Guard
Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Learning from small samples
Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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The Diving Dutchman: het marien-gravimetrisch onderzoek van F.A. Vening Meinesz (1887-1966)
Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra
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Progressive Indexes
Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…
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Software developments in automated structure solution and crystallographic studies of the Sso10a2 and human C1 inhibitor protein
Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu
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Isotopes and the characterization of extrasolar planets
Diverse types of exoplanets such as gas giants on close-in orbits (hot Jupiters) and young massive giants on wide orbits (super Jupiters), with no analogs in the Solar System, pose challenges but also opportunities to our understanding of planet formation and evolution.
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Prosecutorial Discretion in International Criminal Justice
Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.
- About this minor
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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'We overspoelen Aziatische landen met ons plasticafval'
Hoewel veel Nederlanders inmiddels netjes hun plasticafval scheiden, belandt nog steeds een beduidend deel uiteindelijk in de oceaan, aldus ecoloog Arnold Tukker. In een interview met de New Scientist vertelt hij waar het mis gaat.
- ELS lab meeting - Journal Club: Daily surveys on social stressors at work and their influence on marital behaviors at home by Helen Pluut
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Leiden in de prijzen voor computational intelligence
Het Leiden Institute of Advanced Computer Science feliciteert alumnus Pepijn van Heiningen en de met de Technische Hochschule Köln gedeelde promovenda Samineh Bagheri. Allebei wonnen ze afgelopen week op het SSCI 2016 congres over computational intelligence in Athene een award voor de hoge kwaliteit…
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Studenten gaan thuis op excursie naar het Bio Science Park
Sinds 2015 organiseert de Stichting Betabanenmarkt (BBM) jaarlijks de Bio Science Park Excursie om studenten kennis te laten maken met de wereld van start-ups en techbedrijven die zich om de hoek van de faculteit Wiskunde en Natuurwetenschappen bevinden. Dit jaar was het niet mogelijk om het Bio Science…
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Post-kwantumcryptografie moet onze bankrekening, DigiD en staatsgeheimen veilig houden
Jouw bankzaken, DigiD, en gevoelige medische gegevens: wat als onze volledige digitale infrastructuur niet meer te vertrouwen is? Met die vraag in zijn achterhoofd is promovendus Jelle Don dagelijks bezig met zijn onderzoek. En dat is hard nodig, want zonder nieuwe digitale veiligheidsmaatregelen is…
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Duurzame toekomst
Hoe kunnen we onze maatschappij zo inrichten dat de wereld leefbaar blijft voor onszelf en al het andere leven om ons heen? Aan dat vraagstuk werken Leidse wetenschappers samen vanuit allerlei disciplines, van biologie tot datawetenschap en van milieueconomie tot archeologie.
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Kegge en Kremers geven een lezing over voorzorgsbeginsel in de Habitatrichtlijn
Op donderdag 9 september 2021 namen Rogier Kegge en Hidde Kremers deel aan The 8th Annual Conference of The European Environmental Law Forum in Bournemouth (online).
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Flexibilisering, Globalisering en Technologische Vooruitgang: Gevolgen voor Arbeidsmarkt en Sociale Zekerheid.
Dit onderzoeksproject wordt mogelijk gemaakt door een onderzoekssubsidie van Instituut Gak.
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Interview met Professor Ken Meier: 'Protesten, een representatieve overheid en de rol van leiderschap'
Professor Ken Meier is een van de meest vooraanstaande bestuurskundigen van de wereld. Meier is professor Public Management bij Cardiff School of Business (Wales), professor Bureaucracy and Democracy bij Leiden Universiteit, onderzoeker bij Danish Centre for Social Sciences Research (Kopenhagen, Denemarken)…
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Franco Donati
Wiskunde en Natuurwetenschappen
f.donati@cml.leidenuniv.nl | +31 71 527 2727
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Publicaties
Publicaties die verschijnen in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus.
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Ralph Kijk in de Vegte
Administratief Shared Service Centre
r.kijk.in.de.vegte@assc.leidenuniv.nl | +31 71 527 2727
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Crossing Boundaries
Dit boek beschrijft 20 jaar samenwerking tussen de Filippijnse Isabela University en de Universiteit Leiden in het veldstation Cagayan Valley Programme on Environment and Development (CVPED).